Navigating Semaglutide Use When Planning for Pregnancy

Introduction

The journey toward parenthood is often envisioned as a beautiful, straightforward path, yet for many, it involves careful planning, health considerations, and informed decisions. As individuals increasingly seek effective solutions for weight management and metabolic health, medications like semaglutide have emerged as powerful tools. These advancements, while transformative for many, naturally bring forth new questions, especially for those contemplating conception. The desire to build a family often intersects with personal health goals, making it crucial to understand how modern treatments fit into this delicate balance.

At TrimRx, we recognize that your health journey is deeply personal and complex. Our mission began with a shared vision to help individuals embrace healthier lifestyles by merging cutting-edge telehealth innovations with effective weight loss solutions. We understand the profound questions that arise when personal health management, particularly concerning medications like semaglutide, intersects with the deeply personal aspiration of starting or expanding a family. We believe that sustainable weight loss should be achieved through science, empathy, and a transparent approach, providing a user-friendly and supportive space where individuals receive personalized, medically supervised care. This care is designed to make sustainable weight loss attainable and tailored to each unique journey.

This comprehensive guide is crafted to illuminate the critical considerations for anyone asking, “can I take semaglutide while trying to get pregnant?” We will delve into the science behind semaglutide, its profound impact on weight and fertility, and, most importantly, the expert recommendations for safe family planning. We’ll explore why achieving a healthy weight is beneficial for conception and pregnancy, the current understanding of semaglutide’s effects during gestation, and the practical steps to take if you are considering or actively trying to conceive. By the end of this article, you will gain a clearer understanding of how to navigate this important aspect of your health and family planning, ensuring that your journey is as safe and informed as possible.

Understanding Semaglutide and Its Role in Health

Semaglutide is a medication that has garnered significant attention for its efficacy in managing type 2 diabetes and promoting weight loss. Belonging to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists, semaglutide mimics the action of a natural hormone in the body called GLP-1. This hormone plays a vital role in regulating appetite, insulin production, and blood sugar levels.

How Semaglutide Works in the Body

The mechanism of action for semaglutide is multifaceted, contributing to its broad therapeutic benefits:

• Appetite Suppression: Semaglutide acts on specific receptors in the brain, helping to reduce hunger signals and increase feelings of fullness. This leads to a natural decrease in caloric intake.
• Delayed Gastric Emptying: By slowing down the rate at which food leaves the stomach, semaglutide helps you feel fuller for longer, further supporting appetite control and reducing overall food consumption.
• Improved Insulin Sensitivity: For individuals with type 2 diabetes, semaglutide stimulates insulin release only when blood sugar levels are high, and it also reduces glucagon secretion, which helps lower liver glucose production. This combined effect contributes to better blood sugar control.

Brand Names and Primary Uses

Semaglutide is available under various brand names, each approved for specific indications:

• Ozempic®: An injectable form primarily prescribed for adults with type 2 diabetes to improve blood sugar control and reduce the risk of major cardiovascular events. Many patients also experience weight loss as a beneficial side effect.
• Rybelsus®: The first oral form of semaglutide, also used to improve blood sugar control in adults with type 2 diabetes.
• Wegovy®: An injectable form specifically approved for chronic weight management in adults who are overweight or obese and have at least one weight-related comorbidity.

At TrimRx, we are committed to offering comprehensive, personalized weight loss solutions. Our programs feature [Compounded Semaglutide], [Oral Semaglutide], [Ozempic®], and [Wegovy®] as part of our medically supervised approach. These prescription medications are carefully selected to provide effective support for individuals striving to achieve their health goals. We pride ourselves on partnering exclusively with FDA-registered and inspected pharmacies for the shipping of these weight loss medications, ensuring that quality and safety remain our top priorities for our members.

The Interplay Between Weight, Fertility, and GLP-1 Agonists

The connection between body weight, metabolic health, and fertility is profound and well-documented. For many individuals, managing weight effectively can be a significant step toward improving reproductive health.

Obesity’s Impact on Fertility

Carrying excess weight can present numerous challenges to fertility for both men and women:

• For Women: Obesity often leads to hormonal imbalances, particularly affecting estrogen and androgen levels. This can disrupt the regularity of menstrual cycles, leading to infrequent or absent ovulation (anovulation), a common cause of infertility. Conditions like Polycystic Ovary Syndrome (PCOS), which is a leading cause of female infertility, are often exacerbated by obesity. Fat cells produce estrogen, and an excess of these cells can create a hormonal environment that signals the body as if it’s already pregnant, hindering conception.
• For Men: Excess weight can negatively impact male fertility by suppressing hormones essential for sperm production and health. It can lead to lower testosterone levels, reduced sperm count, decreased sperm motility, and increased DNA fragmentation in sperm, all of which can make conception more difficult.

These factors underscore the critical importance of achieving a healthy weight as a foundational step in family planning. The health risks associated with obesity during pregnancy are also significant, including increased chances of gestational diabetes, pre-eclampsia, hypertension, and complications during labor and delivery.

How Weight Loss Can Boost Fertility

Even modest weight loss—often as little as 5% to 10% of body weight—can dramatically improve reproductive outcomes. This improvement stems from several physiological changes:

• Restored Ovulatory Cycles: For women with irregular periods or PCOS, weight loss can help regulate hormones, leading to more predictable ovulation and improved chances of natural conception.
• Enhanced Hormone Balance: Reducing excess body fat can normalize hormone levels, including those vital for reproductive function in both sexes.
• Better IVF Outcomes: For those undergoing assisted reproductive technologies like IVF, achieving a healthier weight can increase success rates and reduce the risk of pregnancy complications.

This is where GLP-1 agonists like semaglutide can play a supportive role before conception. By facilitating significant weight loss, these medications can indirectly contribute to a more fertile environment.

The “Ozempic Baby” Phenomenon

The rise in popularity of GLP-1 agonists has coincided with anecdotal reports and emerging observations of unexpected pregnancies among individuals using these medications. This phenomenon has playfully been dubbed “Ozempic babies” on social media. While GLP-1 agonists are not fertility treatments, their ability to facilitate weight loss can inadvertently boost fertility. For someone who has struggled with weight-related infertility, restoring hormonal balance and regular ovulation through weight reduction can make conception possible when it previously wasn’t.

Beyond weight loss, these medications may also:

• Decrease Inflammation: Chronic inflammation, often linked to obesity, can negatively impact reproductive health. GLP-1 agonists may help reduce this inflammatory burden.
• Regulate Testosterone Levels: For women with PCOS, elevated testosterone levels can interfere with ovulation. Weight loss and improved metabolic health can help normalize these levels.
• Encourage Ovulation: The overall improvement in metabolic health can create a more favorable environment for regular ovulation.

It is crucial to emphasize that GLP-1 agonists are primarily approved for managing diabetes and obesity, not as fertility drugs. While they may have a beneficial secondary effect on fertility by promoting weight loss, they should not be considered a “magic potion” for infertility. For those actively trying to conceive, the primary goal should be to achieve a healthy weight and then, importantly, to transition off these medications with medical guidance before conception.

If you are curious about how a personalized weight management program could impact your overall health and potentially support your family planning goals, we invite you to [take our free assessment quiz] today. This quiz will help us determine your eligibility for our prescription weight loss medications, including [Compounded Semaglutide], [Oral Semaglutide], [Ozempic®], [Compounded Tirzepatide], [Oral Tirzepatide], [Mounjaro®], [Zepbound®], and [Wegovy®].

Semaglutide and Family Planning: What the Research Says

When considering medication use while trying to conceive or during pregnancy, safety is paramount. For semaglutide, a clear picture is emerging regarding its use in family planning.

Current Recommendations for Pregnancy Planning

The most critical recommendation from regulatory bodies like the FDA and leading medical associations is clear: individuals planning a pregnancy should discontinue semaglutide at least two months before attempting to conceive. This applies to all forms of semaglutide, whether [Compounded Semaglutide], [Oral Semaglutide], or branded options like [Ozempic®] and [Wegovy®]. At TrimRx, we echo this expert advice, extending it to other GLP-1 medications such as [Compounded Tirzepatide], [Oral Tirzepatide], [Mounjaro®], and [Zepbound®].

Why the Two-Month Washout Period?

The recommendation for a two-month washout period is based on the drug’s pharmacokinetic properties. Semaglutide has a relatively long half-life, meaning it takes a significant amount of time for the body to metabolize and eliminate the medication. On average, it takes up to six weeks for most of the semaglutide to be gone from the body in healthy non-pregnant adults. The two-month recommendation provides an ample safety margin, ensuring the drug has cleared the system before conception.

Insights from Animal and Limited Human Studies

Given the ethical complexities of conducting clinical trials on pregnant women, most initial safety data for new medications comes from animal studies.

Animal Study Findings

Manufacturer-conducted animal studies on semaglutide have shown some concerning results:

• Increased Chance of Miscarriage: Animal studies reported a higher chance of miscarriage, though it’s unclear if this was directly due to the medication or related to weight loss occurring in the animals.
• Birth Defects: In some animal studies, an increased chance for certain birth defects was observed. However, this occurred when the amount of semaglutide given was at very high, maternally toxic doses—significantly higher than what would be used in humans.
• Smaller Offspring: Animal studies also reported offspring that were smaller than usual when the parent animal was exposed to high doses.

It is vital to remember that findings in animal studies do not always translate directly to humans. Human physiology differs, and the doses administered in animal studies are often far greater than therapeutic human doses. Nonetheless, these findings necessitate a cautious approach until sufficient human data is available.

Limited Human Observations

Human data on semaglutide use during pregnancy is very limited, primarily consisting of case reports:

• One report involved a woman who became pregnant while taking semaglutide and continued for the first 3-4 weeks of pregnancy, giving birth to a child without reported birth defects.
• A small study involving 168 pregnant women using GLP-1s, including 51 on semaglutide during early pregnancy, did not report an increased chance of major birth defects or pregnancy loss compared to control groups.

While these early human observations are somewhat reassuring, they are far from conclusive. Large-scale, well-controlled studies are needed to definitively assess the safety of semaglutide during pregnancy. For this reason, medical professionals universally advise against its use during gestation.

The Risks of Untreated Conditions During Pregnancy

While the focus is often on medication risks, it’s equally important to consider the risks of untreated underlying conditions, such as obesity and uncontrolled blood sugar, during pregnancy:

• Difficulty Conceiving: As previously discussed, both obesity and uncontrolled diabetes can make it harder to get pregnant.
• Increased Chance of Miscarriage and Birth Defects: High blood sugar levels, particularly in early pregnancy, significantly increase the risk of birth defects and miscarriage.
• Other Pregnancy Complications: Untreated obesity and diabetes can lead to gestational diabetes, pre-eclampsia, preterm delivery, and macrosomia (large baby), which can complicate labor and delivery.

This complex interplay underscores the importance of pre-conception planning. The goal is to optimize maternal health before pregnancy, ideally by achieving a healthy weight and stable blood sugar levels without medications deemed unsafe during gestation. Your healthcare provider will help you weigh the benefits of treating your condition before pregnancy against the risks of untreated illness during pregnancy.

Contraceptive Considerations While on Semaglutide

For those using semaglutide who are not planning to conceive immediately but are of reproductive age, contraception is a crucial topic. GLP-1 agonists, including semaglutide, work by slowing gastric emptying. This mechanism can affect how oral medications, including oral hormonal birth control pills, are absorbed by the body. Slower absorption could potentially reduce the effectiveness of these contraceptives, leading to an unintended pregnancy.

Healthcare providers recommend using backup birth control methods (such as condoms or a vaginal diaphragm) during titration weeks (when increasing your GLP-1 dosage) and potentially throughout the duration of treatment with oral contraceptives. Alternatively, switching to non-oral contraceptive options, such as IUDs (intrauterine devices) or contraceptive implants, which are not affected by gastric emptying, may be a more reliable choice.

At TrimRx, we prioritize your safety and informed decision-making. Our comprehensive service includes doctor consultations where you can discuss all aspects of your health, including family planning and contraceptive needs. We are dedicated to providing unlimited support and guidance throughout your wellness journey.

Navigating Pregnancy While on Semaglutide

Despite careful planning, unexpected pregnancies can occur. If you discover you are pregnant while taking semaglutide, immediate action and medical consultation are essential.

If Pregnancy Occurs Unexpectedly

Should you find yourself pregnant while actively on semaglutide, the primary and most important step is to contact your healthcare provider immediately. Do not self-discontinue the medication without medical advice. Your provider will discuss the risks and benefits based on your individual health profile and the stage of your pregnancy.

The likely recommendation will be to stop the medication due to the lack of sufficient human safety data during pregnancy and the concerns raised by animal studies. While current limited human observations have not reported major impacts from early pregnancy exposure, the medical consensus leans towards caution and discontinuation to help ensure a healthy pregnancy.

Importance of Medical Supervision and Personalized Care

Stopping semaglutide, especially if you have an underlying condition like type 2 diabetes or significant obesity, requires a carefully managed transition. Your healthcare provider will help you:

• Develop a personalized plan: This may involve replacing semaglutide with pregnancy-safe alternatives for blood sugar control (such as insulin for diabetes) or strategies for weight management that are safe during pregnancy.
• Monitor your health closely: Regular monitoring of blood sugar levels (if applicable) and overall well-being will be crucial to manage any changes resulting from discontinuing the medication.
• Provide guidance on nutrition and lifestyle: Support for maintaining a healthy lifestyle, including diet and exercise suitable for pregnancy, will be paramount.

At TrimRx, our brand is built on empathetic, innovative, trustworthy, supportive, results-oriented, and personalized care. We offer compassionate support that respects every individual’s unique journey. Our advanced medical science combined with modern technology ensures that when unexpected situations arise, like an unplanned pregnancy while on treatment, you have access to expert guidance. Our commitment to transparent service means our approach remains consistent, focusing on your safety and well-being. We partner with FDA-registered and inspected pharmacies for the shipping of weight loss medications, further underscoring our dedication to safety and quality, though it is important to clarify that TrimRx partners with these pharmacies for medication shipping and does not provide actual medical supervision.

If you have questions about your current medication regimen or wish to discuss how our personalized programs can support your health goals safely, we encourage you to [take our free assessment quiz]. It’s the first step toward a customized plan designed with your unique needs in mind.

Semaglutide Use Postpartum and During Breastfeeding

The journey of health management continues beyond pregnancy, especially for new mothers. Decisions about resuming semaglutide, or other GLP-1 agonists, postpartum and during breastfeeding require careful consideration and medical guidance.

Breastfeeding Recommendations While on Semaglutide

Information regarding semaglutide and human breast milk is limited. Here’s what current data and recommendations suggest:

• Limited Human Data: There are few studies on semaglutide levels in human breast milk. One study involving eight breastfeeding women found semaglutide was not detected in breast milk after injections of up to 1.0 mg per week. However, general expectations based on animal studies suggest semaglutide could get into breast milk in small amounts.
• Theoretical Concerns for Oral Semaglutide (Rybelsus®): The product label for Rybelsus® (oral semaglutide) recommends that women who are breastfeeding not use the tablet form of the medication. This is due to a theoretical concern that the oral form could lead to higher levels of semaglutide in a nursing infant, as there is no published data on its use during breastfeeding.
• Healthcare Provider Consultation: Your healthcare providers will discuss the benefits of using semaglutide for your postpartum health against any possible risks to your breastfed infant. They can help you make an informed decision about the best treatment for you and your baby while breastfeeding. Typically, stopping semaglutide during breastfeeding is often recommended until more conclusive data on infant safety is available.

Our personalized programs are designed to provide continuous support through every life stage. If you’re navigating postpartum health and considering weight management options, our team can help you understand all available choices.

Resuming Semaglutide Post-Breastfeeding

Once you have completed your breastfeeding journey and are ready to consider resuming weight management medications, a gradual approach is typically recommended:

• Restarting at the Smallest Dose: Even if you were on a higher dose before pregnancy, it is generally advised to restart semaglutide at the smallest possible dose. The gastrointestinal system needs time to readjust, and abruptly returning to higher doses can lead to uncomfortable side effects.
• Gradual Titration: Your provider will guide you through a slow titration process, gradually increasing the dose over weeks or months. This allows your body to adapt and minimizes side effects.
• Addressing Potential Weight Regain: It’s common for individuals to experience some weight regain after discontinuing semaglutide during pregnancy. Resuming the medication, combined with continued lifestyle modifications (balanced diet, regular exercise, stress management), can help you get back on track with your weight management goals.
• Impact on Comorbidities: Be mindful that if weight-related comorbidities like joint pain or sleep apnea improved significantly with initial weight loss, these conditions might worsen if weight is regained. Resuming medication can help improve these again as weight management progresses.

At TrimRx, our comprehensive service includes doctor consultations, medication (if prescribed after qualification), lab work, unlimited support, and shipping with no hidden fees. We are here to support your health journey with continuity, adapting your plan as your life and health needs evolve. For those seeking immediate support for overall wellness during the weight loss journey, we also offer [GLP-1 Daily Support] and [Weight Loss Boost] supplements, available for immediate purchase without requiring a quiz.

The Male Perspective: Semaglutide and Male Fertility

While much of the discussion around medication and pregnancy planning naturally centers on women, it’s also important to consider the potential impact of medications like semaglutide on male fertility.

Current Understanding of Male Fertility and Semaglutide

• Limited Human Studies: Similar to women, extensive human studies investigating the direct effects of semaglutide on male fertility (sperm quality, ability to conceive) or the risk of birth defects attributable to paternal exposure are currently lacking.
• Animal Study Insights: One animal study on male fertility reported no changes at doses of semaglutide that would be equivalent to human therapeutic doses. This suggests a potentially lower risk compared to the findings in female animal models.
• General Paternal Exposure Principles: In general, the consensus in reproductive medicine is that exposures experienced by fathers or sperm donors are less likely to increase risks to a pregnancy compared to maternal exposures. This is because the father’s contribution to the pregnancy is through sperm, which carries genetic material but is less directly involved in the sustained physiological environment of pregnancy and fetal development compared to the mother’s body.

While current data does not indicate a significant concern for male fertility or increased birth defect risk from paternal semaglutide use, open communication with a healthcare provider is always recommended. If a male partner is on semaglutide and the couple is planning to conceive, discussing this with a doctor ensures all aspects of family planning are covered.

At TrimRx, our personalized approach considers the holistic health of individuals. We believe in providing comprehensive information and support for all our members as they navigate their unique health goals, including family planning discussions. We are here to provide empathetic, innovative, and trustworthy guidance every step of the way.

A Personalized Approach to Weight Management and Family Planning with TrimRx

Embarking on a family planning journey while managing your health requires a thoughtful, informed, and personalized strategy. At TrimRx, we are uniquely positioned to support you through this delicate balance, merging the power of cutting-edge telehealth with deeply empathetic, medically supervised care.

Prioritizing Pre-Conception Health

The overarching message for anyone considering “can I take semaglutide while trying to get pregnant” is to prioritize pre-conception health. Achieving a healthier weight before conception can significantly improve your chances of getting pregnant, reduce pregnancy complications, and contribute to a healthier outcome for both you and your baby. This proactive approach ensures that your body is in the best possible condition for the demands of pregnancy.

TrimRx’s Commitment to Your Journey

Our journey at TrimRx began with a shared vision to help individuals embrace healthier lifestyles by merging cutting-edge telehealth innovations with effective weight loss solutions. We understand that every individual’s path is unique, especially when it involves significant life milestones like family planning. Our platform is a user-friendly and supportive space where individuals receive personalized, medically supervised care—all designed to make sustainable weight loss attainable and tailored to the individual.

We are founded on the belief that sustainable weight loss should be achieved through science, empathy, and a transparent approach. This philosophy guides every aspect of our service, from the initial consultation to ongoing support. Our brand personality—empathetic, innovative, trustworthy, supportive, results-oriented, and personalized—is reflected in our commitment to combining advanced medical science with modern technology to deliver compassionate care.

Our Personalized Weight Loss Programs

For those whose health journey includes prescription weight loss medications, we offer a robust program featuring [Compounded Semaglutide], [Oral Semaglutide], [Ozempic®], [Compounded Tirzepatide], [Oral Tirzepatide], [Mounjaro®], [Zepbound®], and [Wegovy®]. To ensure these powerful tools are right for you and align with your family planning goals, we require an initial assessment.

Your Next Step: We encourage you to [take our free assessment quiz] to see if you qualify for our personalized prescription weight loss medications. This quiz is designed to gather essential information about your health history and goals, allowing our medical professionals to craft a safe and effective treatment plan tailored specifically for you and your family planning considerations.

Our comprehensive service goes beyond just medication. It includes:

• Doctor Consultations: Connect with qualified healthcare providers who understand the nuances of weight management and family planning.
• Medication: Access to prescription medications, provided through FDA-registered and inspected pharmacies, ensuring quality and safety. We clarify that while branded medications like Ozempic® and Zepbound® are FDA-approved, compounded medications are not FDA-approved, though they are shipped through our FDA-registered and inspected partner pharmacies.
• Lab Work: Essential diagnostics to monitor your health and ensure the safety and effectiveness of your plan.
• Unlimited Support: Ongoing guidance and answers to your questions, ensuring you never feel alone in your journey.
• Shipping: Convenient delivery of medications directly to your door, with no hidden fees.

Our commitment to transparent service means our approach remains consistent, regardless of dosage changes. Your safety and well-being are always our top priority.

Immediate Support with Quick-Access Supplements

Recognizing that some individuals may be looking for immediate ways to support their wellness during their weight loss journey, particularly as they prepare for pregnancy, we offer quick-access supplements that do not require a quiz:

• [GLP-1 Daily Support]: Designed to complement your body’s natural processes, supporting overall metabolic health.
• [Weight Loss Boost]: Formulated to enhance your weight loss efforts alongside a healthy diet and exercise.

These supplements can provide valuable support as you focus on optimizing your health and preparing your body for conception.

Conclusion

The decision to grow your family is one of life’s most significant journeys, intertwined with personal health and wellness. For those considering “can I take semaglutide while trying to get pregnant,” the answer is nuanced but clear: semaglutide offers considerable benefits for weight management and metabolic health, which can positively impact fertility before conception. However, due to limited data on its safety during pregnancy, medical experts strongly recommend discontinuing semaglutide at least two months before attempting to conceive.

Achieving a healthy weight prior to pregnancy is a powerful step towards a healthier outcome for both parent and child. This period of preparation is an opportune time to focus on establishing sustainable lifestyle habits—including a balanced diet, regular exercise, and effective stress management—which will serve as cornerstones for your health throughout pregnancy and beyond.

At TrimRx, we stand as your dedicated partner, committed to supporting your holistic health journey with science, empathy, and transparent care. We understand that your path is unique, and we are here to provide the personalized, medically supervised solutions you need, ensuring every decision is made with safety and your well-being at its heart. Whether you are actively planning for pregnancy, managing your weight, or seeking overall wellness, we offer the tools and support to help you achieve your goals.

We encourage you to embark on this journey with confidence and informed choices. Discover how our personalized programs can support your health and family planning aspirations by taking our [free assessment quiz] today. For immediate wellness support, explore our [GLP-1 Daily Support] and [Weight Loss Boost] supplements, designed to complement your efforts. Your healthier future, and your family’s, starts with a clear, supportive path forward.

Frequently Asked Questions (FAQs)

Q1: How long before trying to conceive should I stop taking semaglutide?

A1: Healthcare providers, including those at TrimRx, strongly recommend discontinuing semaglutide at least two months (approximately eight weeks) before you start actively trying to conceive. This “washout” period allows the medication to clear your system due to its relatively long half-life, ensuring it is no longer active in your body by the time of conception. This recommendation applies to all forms of semaglutide (e.g., [Compounded Semaglutide], [Oral Semaglutide], [Ozempic®], [Wegovy®]) and other GLP-1 medications like [Compounded Tirzepatide], [Oral Tirzepatide], [Mounjaro®], and [Zepbound®].

Q2: Can semaglutide make it harder or easier to get pregnant?

A2: Semaglutide is not a fertility treatment. However, by facilitating significant weight loss, it can indirectly make it easier to get pregnant for individuals whose fertility has been impacted by obesity or conditions like PCOS. Achieving a healthier weight can help regulate hormones, restore ovulatory cycles, and improve overall reproductive health. Conversely, the medication itself is not known to directly make it harder to get pregnant, but its use during conception efforts is not advised due to safety concerns for the pregnancy.

Q3: What if I become pregnant while taking semaglutide?

A3: If you discover you are pregnant while taking semaglutide, you should contact your healthcare provider immediately. It is generally recommended to discontinue the medication due to limited human safety data during pregnancy and concerns from animal studies. Your provider will guide you on the safest course of action, which may include transitioning to pregnancy-safe alternatives for managing any underlying health conditions like diabetes or obesity, and will provide a personalized plan for monitoring your health throughout your pregnancy.

Q4: Is it safe to breastfeed while on semaglutide?

A4: Information regarding semaglutide in human breast milk is limited. While some small studies suggest it may not be detectable in breast milk after injection, the product label for oral semaglutide (Rybelsus®) recommends against its use while breastfeeding due to theoretical concerns of higher infant exposure. Your healthcare provider can discuss the specific benefits and risks of continuing semaglutide versus stopping it during breastfeeding, helping you make the most informed decision for both your health and your baby’s well-being.