Exploring Semaglutide for Weight Loss: Can I Take Semaglutide If I Am Not Diabetic?

Introduction

The quest for sustainable weight management often feels like navigating a complex maze, particularly for the millions of individuals facing the persistent challenges of being overweight or having obesity. While diet and exercise form the cornerstone of any wellness journey, for many, these efforts alone may not be enough to achieve significant, lasting results. This reality has spurred continuous innovation in medical science, leading to breakthroughs that offer new hope. One such innovation that has captured considerable attention is semaglutide, a medication initially recognized for its role in managing Type 2 diabetes. However, its profound effects on weight loss have broadened its application, raising a crucial question for many: “Can I take semaglutide if I am not diabetic?”

At TrimRx, our journey began with a shared vision to empower individuals to embrace healthier lifestyles by merging cutting-edge telehealth innovations with effective weight loss solutions. We believe that sustainable weight loss should be achieved through science, empathy, and a transparent approach. This commitment drives us to provide comprehensive, medically supervised care that is both personalized and accessible. This article aims to demystify semaglutide’s utility for non-diabetic individuals seeking effective weight management. We will delve into how semaglutide works, explore the scientific evidence supporting its use in non-diabetic populations, outline eligibility criteria, discuss what a treatment journey entails, and highlight the supportive, results-oriented, and personalized approach we offer at TrimRx. By the end of this discussion, you will gain a clear understanding of whether semaglutide could be a valuable tool in your weight loss journey, guided by an empathetic and trustworthy perspective that champions your unique path to wellness.

Understanding Semaglutide: More Than Just for Diabetes

Semaglutide represents a significant advancement in metabolic medicine. Its origin lies in diabetes management, yet its broader physiological impacts have positioned it as a powerful ally in the fight against obesity. To truly grasp its potential, particularly for those without diabetes, it’s essential to understand what semaglutide is and how its therapeutic reach has expanded.

What is Semaglutide?

At its core, semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. This means it mimics the action of a naturally occurring hormone in your body called GLP-1. This hormone plays a vital role in several bodily functions related to digestion and metabolism. When you eat, your gut releases GLP-1, which signals your brain and other organs. Semaglutide essentially amplifies these natural signals.

Initially, semaglutide was developed to help adults with Type 2 diabetes manage their blood sugar levels. It achieves this primarily by stimulating insulin release from the pancreas when blood sugar is high and by reducing the production of glucagon, a hormone that raises blood sugar. It also slows down gastric emptying, meaning food stays in your stomach longer, which helps prevent sharp spikes in blood sugar after meals. Beyond these effects, it was observed that patients taking semaglutide often experienced significant weight loss. This observation catalyzed further research, shifting its perception from solely a diabetes medication to a promising weight management solution. Our commitment at TrimRx is rooted in leveraging such scientific innovations to offer effective and safe pathways to better health.

The Evolution to Weight Management

The journey of semaglutide from a diabetes treatment to a weight loss medication is a testament to rigorous scientific inquiry. Clinical trials involving individuals with obesity, both with and without Type 2 diabetes, consistently demonstrated its remarkable efficacy in reducing body weight. These studies were instrumental in establishing semaglutide’s role beyond glycemic control.

Recognizing these compelling results, the U.S. Food and Drug Administration (FDA) approved a specific formulation of semaglutide, known as Wegovy®, for chronic weight management in adults. This approval marked a pivotal moment, officially sanctioning semaglutide as a dedicated treatment for obesity and overweight with weight-related conditions. While Wegovy® is the only brand name semaglutide explicitly FDA-approved for weight loss, other semaglutide products like Ozempic® and Rybelsus®, which are FDA-approved for Type 2 diabetes, are sometimes prescribed off-label by healthcare professionals for weight management when deemed medically appropriate. This practice is supported by extensive research showing the core mechanism of semaglutide’s weight-reducing effects is consistent across populations, irrespective of diabetes status. We at TrimRx prioritize working within these medical guidelines, ensuring that any prescription aligns with the latest clinical understanding and individual patient needs.

Can Non-Diabetics Benefit from Semaglutide for Weight Loss?

The question “can I take semaglutide if I am not diabetic?” is at the forefront of many individuals’ minds as they explore modern weight loss solutions. The resounding answer from clinical research and medical practice is yes, many non-diabetic individuals can indeed benefit from semaglutide for weight loss, provided they meet specific health criteria and receive appropriate medical supervision.

The Scientific Evidence for Non-Diabetics

Extensive research underscores the safety and effectiveness of semaglutide in individuals without Type 2 diabetes. A 2022 review, for instance, indicated that semaglutide injections are a safe and effective option for weight loss in this population. The fundamental way semaglutide works in the body—by mimicking the GLP-1 hormone to influence appetite and satiety—is universal, affecting individuals whether they have diabetes or not. This means the mechanisms leading to reduced food intake and subsequent weight loss are active regardless of a person’s glycemic status.

Trials like the OASIS 1 study, which specifically assessed oral semaglutide in non-diabetic individuals with overweight or obesity, showcased remarkable results. Participants experienced an average weight reduction of 15.1% over 68 weeks. Other clinical trials have also reported significant reductions in body weight, often averaging between 11.85% and 15% from baseline. These studies not only confirm the weight loss efficacy but also highlight improvements in cardiometabolic risk factors such as blood pressure and cholesterol levels, offering a holistic benefit that extends beyond just shedding pounds. This scientific foundation reinforces our belief at TrimRx in offering clinically proven solutions for personalized weight management.

Who Qualifies: Eligibility Criteria

While semaglutide offers significant promise, it is not a universally prescribed solution. Eligibility for semaglutide for weight loss, especially for non-diabetic individuals, is determined by specific medical criteria established by health authorities like the FDA. Generally, adults are considered candidates if they meet one of the following:

• A Body Mass Index (BMI) of 30 kg/m² or greater (considered obesity).
• A BMI of 27 kg/m² or greater (considered overweight) accompanied by at least one weight-related medical condition. These conditions can include high blood pressure, dyslipidemia (abnormal levels of lipids in the blood), or prediabetes.

It’s crucial to understand that these are general guidelines, and a comprehensive medical evaluation is always necessary. This evaluation includes reviewing your medical history, current health status, and any existing conditions to ensure that semaglutide is a safe and appropriate option for you. At TrimRx, we streamline this process with our free assessment quiz. This initial step helps us understand your unique health profile and determine your eligibility for our personalized prescription weight loss medications. We believe that every individual’s journey is unique, and our approach respects this by combining advanced medical science with compassionate care to tailor a plan that truly fits your needs. Take our free assessment quiz today to see if you qualify for our personalized weight loss programs.

How Semaglutide Works in the Body for Weight Loss

The effectiveness of semaglutide for weight loss stems from its intricate interaction with several physiological pathways, primarily centered around its role as a GLP-1 receptor agonist. Understanding these mechanisms helps illuminate why it’s such a transformative tool, even for individuals who are not diabetic.

Mimicking GLP-1: The Core Mechanism

The core mechanism of semaglutide lies in its ability to mimic the glucagon-like peptide-1 (GLP-1) hormone. GLP-1 is a natural incretin hormone produced in the gut in response to food intake. Its physiological effects are widespread, influencing glucose metabolism, gastric motility, and appetite regulation. When semaglutide enters the body, it binds to GLP-1 receptors in various tissues, including the pancreas, gut, and brain. By activating these receptors, semaglutide initiates a cascade of effects that collectively contribute to weight reduction.

One of its key actions is stimulating the release of insulin from pancreatic beta cells in a glucose-dependent manner. This means insulin is released primarily when blood sugar levels are elevated, helping to lower glucose without significantly increasing the risk of low blood sugar (hypoglycemia) in non-diabetic individuals. Simultaneously, semaglutide suppresses glucagon secretion from pancreatic alpha cells, preventing the liver from releasing excessive glucose. This dual effect on insulin and glucagon helps maintain stable blood sugar levels. Furthermore, semaglutide slows down gastric emptying, prolonging the feeling of fullness after meals, which is a critical factor in appetite control.

Impact on Appetite and Satiety

Perhaps the most impactful aspect of semaglutide for weight loss in non-diabetic individuals is its profound effect on appetite and satiety. The GLP-1 receptors in the brain, particularly in areas that regulate appetite and reward pathways, are highly responsive to semaglutide.

When semaglutide activates these receptors, it leads to several significant changes in eating behavior:

• Reduced Appetite and Cravings: Many individuals report a noticeable decrease in hunger sensations and cravings for certain foods, especially those high in fat or sugar. This makes it easier to adhere to a reduced-calorie diet without feeling constantly deprived.
• Increased Satiety: By slowing gastric emptying, semaglutide ensures that food remains in the stomach for a longer duration. This mechanical effect, combined with the hormonal signals sent to the brain, translates into a prolonged feeling of fullness or satiety. Individuals feel satisfied with smaller portions and are less prone to snacking between meals.
• Altered Food Preferences: Some studies suggest that semaglutide may also influence food preferences, leading individuals to naturally gravitate towards healthier food choices and away from highly palatable, calorie-dense options.

These combined effects empower individuals to make sustainable dietary changes, reducing overall caloric intake without the intense struggle often associated with traditional dieting. It’s about recalibrating the body’s natural hunger and fullness cues, providing a powerful support system for weight loss.

Metabolic Benefits Beyond Weight Loss

The advantages of semaglutide extend beyond simply shedding pounds. The improvements in weight often bring about a ripple effect of positive metabolic changes, which are highly beneficial for overall health, particularly in non-diabetic individuals.

• Improved Cardiometabolic Markers: Weight loss itself can lead to significant improvements in various cardiometabolic risk factors. Semaglutide contributes to this by helping to lower blood pressure, reduce unhealthy cholesterol levels (LDL cholesterol and triglycerides), and improve insulin sensitivity. These effects are crucial for reducing the risk of cardiovascular diseases, which are often co-morbidities of obesity.
• Reduced Risk of Heart Events: In clinical trials focusing on Type 2 diabetic patients with cardiovascular disease, semaglutide demonstrated a reduction in the risk of major cardiovascular events, such as heart attacks and strokes. While primarily studied in diabetic populations, these benefits underscore the medication’s protective effects on the cardiovascular system, which can extend to non-diabetic individuals experiencing weight-related metabolic stress.
• Enhanced Glucose Regulation: Even in non-diabetic individuals, semaglutide’s influence on glucose metabolism can be beneficial. It helps to stabilize blood sugar levels, which can be advantageous for those with prediabetes or those at risk of developing Type 2 diabetes.

At TrimRx, we recognize that true wellness encompasses more than just a number on the scale. Our personalized programs are designed to support a holistic approach to health, focusing on these broader metabolic benefits as integral components of a healthier lifestyle. We believe that by merging innovative treatments with comprehensive care, we can help individuals achieve not just weight loss, but a significant improvement in their overall well-being.

Navigating Treatment: What to Expect

Embarking on a weight loss journey with semaglutide, particularly for non-diabetic individuals, involves understanding the various product options, the treatment process, and potential considerations. Our goal at TrimRx is to provide a clear, supportive, and results-oriented path.

Types of Semaglutide and Related Medications

The landscape of GLP-1 receptor agonists and related medications offers several options, each with distinct characteristics and approvals. For individuals considering semaglutide for weight loss without diabetes, it’s important to differentiate these:

• Ozempic® (Semaglutide Injection): This is a once-weekly subcutaneous injection primarily FDA-approved for improving blood sugar control in adults with Type 2 diabetes and reducing the risk of major cardiovascular events in adults with Type 2 diabetes and established heart disease. While not FDA-approved for weight loss in non-diabetics, healthcare providers may prescribe it off-label for this purpose based on their clinical judgment.
• Rybelsus® (Oral Semaglutide): The first oral GLP-1 receptor agonist, Rybelsus® is an FDA-approved daily tablet for adults with Type 2 diabetes to improve blood sugar. Similar to Ozempic®, it can be prescribed off-label for weight management by medical professionals.
• Wegovy® (Semaglutide Injection): This once-weekly subcutaneous injection is specifically FDA-approved for chronic weight management in adults with obesity (BMI ≥30) or overweight (BMI ≥27) with at least one weight-related condition. This is the only branded semaglutide product approved solely for weight loss.
• Compounded Semaglutide (Injection/Oral): Compounded versions of semaglutide are available through FDA-registered and inspected pharmacies. It’s important to note that compounded medications are not FDA-approved products themselves; rather, they are custom-prepared by licensed pharmacies to meet individual patient needs, in compliance with state and federal regulations. At TrimRx, we partner exclusively with FDA-registered and inspected pharmacies to ensure the highest standards of safety and quality for all medications, including compounded semaglutide, provided through our programs.
• Mounjaro® (Tirzepatide Injection): Tirzepatide is a novel medication that acts as both a GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. Mounjaro® is FDA-approved for improving blood sugar control in adults with Type 2 diabetes. Like Ozempic®, it may be prescribed off-label for weight management.
• Zepbound® (Tirzepatide Injection): Zepbound® is the tirzepatide product specifically FDA-approved for chronic weight management in adults with obesity or overweight with at least one weight-related condition.
• Compounded Tirzepatide (Injection/Oral): Similar to semaglutide, compounded versions of tirzepatide are available through our partnerships with FDA-registered and inspected pharmacies. Again, these compounded medications are not FDA-approved, but the pharmacies we work with uphold stringent quality and safety standards.

At TrimRx, our comprehensive Personalized Weight Loss Program encompasses a range of these clinically proven options, including Compounded Semaglutide, Oral Semaglutide, Ozempic®, Compounded Tirzepatide, Oral Tirzepatide, Mounjaro®, Zepbound®, and Wegovy®. To determine which medication, if any, is right for you, we encourage you to take our free assessment quiz. This is the gateway to a personalized treatment plan, developed with medically supervised care and delivered with our hallmark transparency and unwavering support.

Dosage and Administration

The administration of semaglutide, whether oral or injectable, typically begins with a low dose, which is then gradually increased over several weeks or months. This titration process is crucial for two main reasons: to allow your body to adjust to the medication and to minimize potential side effects. The specific dosage regimen will be determined by a qualified healthcare professional, who will consider your individual health profile, weight loss goals, and how you respond to the treatment. This personalized approach is a cornerstone of our service at TrimRx, where a dedicated doctor consultation is an integral part of your program.

Our comprehensive service includes not only the medication (shipped directly from our FDA-registered and inspected partner pharmacies) but also necessary lab work, ongoing unlimited support from our team, and convenient shipping, all with no hidden fees. Our commitment to transparent service means our approach remains consistent, providing you with continuous guidance regardless of any dosage adjustments made by your supervising healthcare professional.

Potential Side Effects and Safety Considerations

Like all medications, semaglutide can cause side effects. Most commonly, these are gastrointestinal in nature and tend to be mild to moderate, especially during the initial phase of treatment when the dose is being gradually increased. Common side effects include:

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Abdominal pain
• Headache
• Fatigue

These symptoms often subside as your body adjusts to the medication. Your healthcare provider will guide you on strategies to manage these side effects, such as adjusting diet or administration timing.

While rare, more serious risks are associated with semaglutide. These include:

• Pancreatitis: Inflammation of the pancreas.
• Gallbladder disease: Including gallstones.
• Acute kidney injury: Particularly if dehydration occurs due to severe vomiting or diarrhea.
• Thyroid C-cell tumors: Including medullary thyroid carcinoma (MTC). Semaglutide is contraindicated in individuals with a personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Prior to starting any treatment, a thorough review of your medical history is conducted to identify any contraindications or predispositions to these risks. At TrimRx, your safety is our utmost priority. We ensure that your weight loss journey is medically supervised by qualified healthcare professionals and that all medications are sourced from FDA-registered and inspected pharmacies, upholding the highest standards of care and compliance. We believe in providing compassionate care that respects every individual’s unique journey, combining advanced medical science with modern technology for your well-being.

The TrimRx Approach to Personalized Weight Loss

At TrimRx, we understand that weight loss is not a one-size-fits-all endeavor. Our approach is deeply rooted in personalization, scientific rigor, and unwavering support, ensuring that every individual receives care tailored to their unique needs and goals.

Our Vision and Values

Our foundation at TrimRx was built on a shared vision: to empower individuals to achieve healthier lifestyles by integrating cutting-edge telehealth innovations with effective, evidence-based weight loss solutions. We envision a world where sustainable weight loss is accessible, safe, and truly individualized. Our platform stands as a user-friendly and supportive space where individuals receive personalized, medically supervised care—all designed to make sustainable weight loss attainable and tailored to the individual.

We are driven by a core belief that sustainable weight loss should be achieved through science, empathy, and a transparent approach. Our brand personality reflects this commitment: we are empathetic, innovative, trustworthy, supportive, results-oriented, and personalized. We offer compassionate care that respects every individual’s unique journey, combining advanced medical science with modern technology to deliver exceptional results. Our dedication to transparent service means that our approach remains consistent and clear, irrespective of dosage changes, and our focus on safety is paramount, as we work exclusively with FDA-registered and inspected pharmacies for the shipping of all weight loss medications.

The Personalized Weight Loss Program

For those seeking prescription weight loss medications like Compounded Semaglutide, Oral Semaglutide, Ozempic®, Compounded Tirzepatide, Oral Tirzepatide, Mounjaro®, Zepbound®, and Wegovy®, your journey with TrimRx begins with a crucial first step: our free assessment quiz. This comprehensive evaluation is designed to determine your eligibility and help our medical team craft a personalized treatment plan that aligns with your health profile and weight loss aspirations.

Our personalized program offers a comprehensive service that includes:

• Doctor Consultations: Connecting you with qualified healthcare professionals who provide expert medical supervision and guidance.
• Medication: Prescription weight loss medications, when appropriate, are provided through our partnerships with FDA-registered and inspected pharmacies. We do not provide actual medical supervision; instead, we facilitate your connection with healthcare professionals and ensure safe medication delivery.
• Lab Work: Essential lab tests to monitor your health and ensure the safety and effectiveness of your treatment.
• Unlimited Support: Our dedicated support team is available to answer your questions and provide encouragement throughout your journey.
• Shipping: Convenient and discreet shipping of your medication directly to your door.

All these components come with no hidden fees, embodying our commitment to transparency. We believe in offering a clear, straightforward path to weight loss, empowering you with the tools and support you need to succeed. Take our free assessment quiz today to start your personalized journey towards a healthier you.

Supporting Your Journey with Quick-Access Supplements

Beyond our prescription programs, we recognize that comprehensive wellness often benefits from immediate, accessible support. For those looking to support their overall health and weight loss journey, we offer a range of quick-access supplements that do not require a medical quiz or prescription:

• GLP-1 Daily Support: This supplement is designed to complement your body’s natural processes, supporting metabolic health and potentially enhancing feelings of fullness.
• Weight Loss Boost: Formulated to provide additional support, this supplement aims to boost your weight management efforts.

These quick-access supplements are available for immediate purchase, offering flexible options to integrate into your daily routine. They are part of our broader commitment to providing diverse tools that cater to various needs and preferences along the path to sustainable weight loss. Whether you’re exploring our prescription programs through the assessment quiz or seeking immediate support, TrimRx is here to empower your journey.

Sustaining Weight Loss: Beyond Medication

While semaglutide and other advanced medications offer a powerful catalyst for weight loss, achieving and maintaining long-term success requires a holistic approach that extends beyond pharmacological intervention. At TrimRx, we emphasize that medication is a tool, not the sole solution, and it works best when integrated into a broader strategy for sustained wellness.

The Role of Lifestyle Modifications

Effective weight management is fundamentally intertwined with lifestyle modifications. Semaglutide can significantly aid in reducing appetite and promoting satiety, making it easier to adopt healthier eating habits and reduce caloric intake. However, for these changes to become permanent and for weight loss to be sustained, they must be consciously integrated into daily life.

• Dietary Changes: Focusing on a balanced diet rich in whole foods, lean proteins, fruits, and vegetables is crucial. Semaglutide helps to diminish cravings and hunger, creating an opportune window to establish new, healthier eating patterns without feeling constant deprivation. This is about learning to nourish your body effectively rather than just restricting food.
• Increased Physical Activity: Regular exercise complements the effects of semaglutide by improving metabolism, building muscle mass, and enhancing overall cardiovascular health. Whether it’s brisk walking, strength training, or other forms of movement, incorporating consistent physical activity into your routine is vital for both weight loss and maintenance.

We view semaglutide as a powerful “tool in the toolbox” for weight management, but it works synergistically with these fundamental lifestyle changes. Our personalized programs at TrimRx integrate support and guidance for cultivating these healthier habits, ensuring that you develop sustainable practices that will serve you long after you achieve your initial weight loss goals.

Long-Term Commitment and Support

Obesity is increasingly recognized as a chronic condition, similar to high blood pressure or diabetes, requiring ongoing management. This means that weight loss is often a long-term journey, not a one-time event. Studies have shown that when semaglutide is discontinued, individuals may regain a significant portion of the weight they lost. This highlights the importance of understanding weight management as a continuous process and preparing for a long-term commitment.

This commitment involves consistent monitoring, ongoing lifestyle adjustments, and sustained support. Our TrimRx program is designed with this long-term perspective in mind. We provide unlimited support and regular check-ins to monitor your progress, address any challenges, and make necessary adjustments to your care plan. We believe that by fostering a supportive partnership, we can help you navigate the complexities of long-term weight management, ensuring that the progress you make is not only significant but also enduring. Our goal is to empower you with the knowledge, tools, and encouragement to maintain your healthier lifestyle and prevent weight regain, solidifying the results you achieve. To understand how our sustained support can benefit your journey, explore our personalized programs by taking our free assessment quiz.

Conclusion

The question “can I take semaglutide if I am not diabetic?” has opened a new chapter in weight management, offering a scientifically backed and medically supervised pathway for countless individuals seeking effective and sustainable weight loss. We’ve explored how semaglutide, a GLP-1 receptor agonist, works by modulating appetite and satiety, leading to significant weight reduction and broader metabolic benefits, even for those without Type 2 diabetes. Eligibility is determined by specific BMI criteria and the presence of weight-related conditions, underscoring the necessity of a personalized medical evaluation.

At TrimRx, our core mission is to empower you on this journey. Our platform embodies our vision of merging cutting-edge telehealth with effective, personalized weight loss solutions, built on the pillars of science, empathy, and transparency. Through our comprehensive programs, we offer access to prescription medications like Compounded Semaglutide, Oral Semaglutide, Ozempic®, Compounded Tirzepatide, Oral Tirzepatide, Mounjaro®, Zepbound®, and Wegovy®, all delivered with the assurance of FDA-registered and inspected pharmacy partnerships, doctor consultations, lab work, unlimited support, and transparent service with no hidden fees. We understand that sustained weight loss extends beyond medication, integrating seamlessly with vital lifestyle modifications and continuous support.

Your journey to a healthier, more vibrant life is unique, and we are here to provide the innovative tools and compassionate guidance you deserve. Discover your personalized weight loss path today by taking our free assessment quiz to see if you qualify for our prescription weight loss medications. Or, to immediately support your overall wellness during your weight loss journey, explore our convenient quick-access GLP-1 Daily Support and Weight Loss Boost supplements.

Frequently Asked Questions

Is semaglutide safe for non-diabetic individuals seeking weight loss?

Yes, clinical studies have shown that semaglutide can be safe and effective for weight loss in non-diabetic individuals who meet specific criteria for obesity or overweight with weight-related conditions. Safety is always paramount, and a thorough medical evaluation by a healthcare professional is essential to determine if semaglutide is appropriate for your individual health profile. Our personalized programs at TrimRx ensure that every patient receives medically supervised care to prioritize their well-being.

What are the eligibility requirements for non-diabetics to take semaglutide for weight loss?

Generally, non-diabetic adults may qualify for semaglutide for weight loss if they have a Body Mass Index (BMI) of 30 kg/m² or greater (obesity), or a BMI of 27 kg/m² or greater (overweight) with at least one weight-related condition such as high blood pressure, high cholesterol, or prediabetes. The exact criteria can vary, so the best way to determine your eligibility is to take our free assessment quiz, which will connect you with a healthcare professional to review your medical history.

How does semaglutide help non-diabetics lose weight?

Semaglutide helps non-diabetics lose weight by mimicking the natural GLP-1 hormone in the body. This action leads to reduced appetite, increased feelings of fullness (satiety), and slowed gastric emptying, which collectively helps to decrease overall caloric intake. These effects make it easier to adhere to a reduced-calorie diet and adopt healthier eating habits, leading to significant and sustained weight loss when combined with lifestyle changes.

What should I expect in terms of side effects if I take semaglutide as a non-diabetic?

The most common side effects of semaglutide, whether you are diabetic or not, are typically gastrointestinal and include nausea, vomiting, diarrhea, constipation, and abdominal pain. These side effects are usually mild to moderate and often lessen as your body adjusts to the medication, especially when the dose is gradually increased. Your healthcare provider will guide you on how to manage any side effects. Our TrimRx program includes unlimited support to help you navigate your treatment journey smoothly.