What Is a Micro Dose of Wegovy for Your Weight Loss Journey

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48 min
Published on
December 2, 2025
Updated on
December 2, 2025
What Is a Micro Dose of Wegovy for Your Weight Loss Journey

Introduction

Many individuals embarking on a weight loss journey experience a unique blend of hope and frustration. Perhaps you’ve diligently tracked calories, embraced new exercise routines, and explored countless dietary strategies, only to find the scale resistant to change, or worse, to see lost weight return with disheartening speed. This persistent challenge, often intertwined with the constant “food noise” – those intrusive thoughts about what to eat, when to eat, and how much – can significantly impact daily life and overall well-being. It’s a testament to the complex nature of weight management, which extends far beyond simple willpower to encompass intricate biological, hormonal, and metabolic factors.

In recent years, a new class of medications, known as GLP-1 receptor agonists, has emerged as a transformative force in how we approach weight loss and metabolic health. These medications, including those with semaglutide as their active ingredient, have shown remarkable efficacy in helping individuals achieve significant and sustainable weight reduction. Among these, Wegovy® stands out, specifically FDA-approved for weight management. As their popularity has grown, so too has the conversation around various dosing strategies, with the term “microdosing” gaining traction in online discussions and personal anecdotes. This term often refers to taking smaller amounts of a medication than typically recommended by manufacturers, with the intention of minimizing side effects or prolonging supply.

At TrimRx, our journey began with a shared vision to help individuals embrace healthier lifestyles by merging cutting-edge telehealth innovations with effective weight loss solutions. Our platform is a user-friendly and supportive space where individuals receive personalized, medically supervised care, all designed to make sustainable weight loss attainable and tailored to the individual. We believe that sustainable weight loss should be achieved through science, empathy, and a transparent approach. When considering concepts like what is a micro dose of Wegovy, it’s vital to understand the medical context, safety considerations, and the importance of personalized, professional guidance.

This post will delve into the concept of “microdosing” GLP-1 medications, particularly in relation to Wegovy, clarifying what it entails and distinguishing it from the medically recommended titration schedules that are a cornerstone of safe and effective treatment. We will explore the mechanisms behind GLP-1s, the reasons individuals might consider adjusting their dosages, and the potential benefits and risks associated with such approaches. Throughout this discussion, we will emphasize the paramount importance of medical supervision and how a personalized program, like those offered at TrimRx, ensures a safe, effective, and supportive path to achieving your weight loss goals. By the end, you’ll have a clearer understanding of how these powerful medications work, why a structured dosing plan is critical, and how taking our free assessment quiz can be your first step towards a truly individualized weight management solution.

Understanding GLP-1 Medications and Their Role in Weight Management

GLP-1 receptor agonists have fundamentally reshaped the landscape of weight management and metabolic health. To truly grasp the conversation around what is a micro dose of Wegovy, it’s essential to first understand how these powerful medications work within your body.

The Science Behind GLP-1s

GLP-1 stands for Glucagon-Like Peptide-1, a naturally occurring hormone produced in your gut in response to eating. GLP-1 receptor agonists are designed to mimic the effects of this natural hormone, leading to several beneficial outcomes for individuals struggling with weight.

Regulating Blood Sugar Levels

One of the primary actions of GLP-1s is to stimulate insulin release from the pancreas when blood sugar levels are high, and simultaneously suppress glucagon secretion. This dual action helps to stabilize blood glucose, making them highly effective for individuals with type 2 diabetes. While some GLP-1 medications like Ozempic® and Mounjaro® are FDA-approved primarily for diabetes management, their profound impact on weight loss has led to their widespread use in broader weight management contexts.

Slowing Gastric Emptying

GLP-1s slow down the rate at which food leaves your stomach. This means you feel fuller for longer after meals, contributing to a reduced calorie intake. This sustained feeling of satiety is a critical factor in successful weight loss, helping to manage hunger cues more effectively.

Impacting Appetite and “Food Noise”

Beyond physical satiety, GLP-1s also influence brain pathways associated with appetite regulation. Many individuals describe a significant reduction in “food noise” – those constant thoughts and cravings related to food that can be so distracting and challenging to overcome. By quieting this internal dialogue, GLP-1s help individuals develop a healthier relationship with food and make more conscious dietary choices. This can be a profound benefit for those who have struggled with persistent cravings and overeating.

Wegovy® and Semaglutide: A Specific Focus

Wegovy® is a specific brand of semaglutide that is FDA-approved for chronic weight management in adults with obesity or overweight with at least one weight-related condition. Semaglutide, the active ingredient, belongs to the GLP-1 class and has demonstrated significant weight loss outcomes in clinical trials. For instance, research has shown that individuals taking semaglutide can achieve an average body weight reduction of approximately 15% over 68 weeks when combined with a healthy diet and regular physical activity. For someone weighing 200 pounds, this translates to a loss of about 30 pounds, a life-changing result for many.

Similarly, other GLP-1 medications containing tirzepatide, such as Zepbound®, which is also FDA-approved for weight loss, have shown even greater efficacy, with some individuals losing over 20% of their body weight. These results highlight the groundbreaking potential of these medications.

However, like all powerful medications, GLP-1s can come with potential side effects, most commonly gastrointestinal issues such as nausea, vomiting, diarrhea, constipation, and indigestion. These side effects are often the driving force behind discussions around adjusting dosages, including the concept of what is a micro dose of Wegovy. Understanding the balance between efficacy and tolerability is paramount, and it underscores the need for a medically supervised and personalized approach to treatment. At TrimRx, we are committed to providing such an approach, ensuring that your journey is as comfortable and effective as possible. If you’re wondering if these solutions are right for you, we encourage you to take our free assessment quiz to explore your personalized treatment options.

Deconstructing the Concept of Microdosing in Weight Loss

The term “microdosing” has historically been associated with psychedelic substances, implying the intake of very small amounts to achieve subtle effects. In the context of weight loss medications like Wegovy®, the term has been adopted to describe taking a dose lower than the manufacturer’s recommended starting or maintenance dose. While the intention behind this practice—often to mitigate side effects—is understandable, it’s crucial to differentiate between an unsupervised, unproven “microdose” and a medically guided, carefully titrated dosing schedule.

What Constitutes a “Micro Dose” in the Context of GLP-1s?

When people talk about what is a micro dose of Wegovy, they generally refer to a dosage of semaglutide that is less than the standard initial dose of 0.25 mg per week, or a smaller increment during the titration phase. For example, some individuals might attempt doses as low as 0.05 mg or 0.1 mg weekly, in contrast to the typical upward titration to a maximum of 2.4 mg per week for Wegovy.

The core idea is to introduce the medication to the body more gradually, hoping to:

  • Reduce side effects: The most common and often dose-dependent side effects of GLP-1s are gastrointestinal. A lower dose might, in theory, lead to fewer or less severe symptoms like nausea, vomiting, or diarrhea, allowing an individual to remain on the medication.
  • Support a tailored approach: Recognizing that every individual responds differently to medication, a very flexible dosing strategy could, in theory, allow for an even more fine-tuned approach to treatment.
  • Maintain weight loss: For individuals who have reached their target weight, some might consider a lower dose to be sufficient for long-term weight maintenance, rather than remaining on the full maintenance dose.

However, it is vital to acknowledge that taking a dose lower than what has been studied and approved by regulatory bodies (like the FDA) for specific indications is considered an “off-label” use. There are currently no official FDA guidelines or robust clinical studies specifically on “microdosing” GLP-1 medications for weight loss. Reports of its efficacy are largely anecdotal, primarily shared on social media platforms, and lack the scientific backing of controlled clinical trials.

The Distinction Between Unsupervised Microdosing and Medically Supervised Titration

This is where the nuances of what is a micro dose of Wegovy become critically important. When embarking on any GLP-1 medication regimen, medical professionals always start patients on the lowest effective dose and gradually increase it over several weeks or months. This process is known as titration.

For Wegovy, the typical starting dose is 0.25 mg once per week, which is then gradually increased to 0.5 mg, 1 mg, 1.7 mg, and finally to the target maintenance dose of 2.4 mg per week, or a lower dose if goals are met and maintained. This gradual increase is precisely designed to allow the body to adjust to the medication, thereby minimizing side effects while still reaching a therapeutically effective dose.

In a medically supervised setting, this initial low dose is essentially a “microdose” compared to the full therapeutic dose. It’s a controlled, evidence-based strategy to ensure patient comfort and adherence. The difference lies in the intent and oversight.

  • Medically Supervised Titration (like at TrimRx): This involves a healthcare provider systematically increasing the dose based on individual response, tolerability, and weight loss goals. The goal is to find the optimal effective dose for each person, not necessarily the lowest possible dose that might not yield therapeutic benefits. This approach is rooted in extensive clinical research and safety protocols.
  • Unsupervised Microdosing: This often involves individuals self-administering doses lower than even the recommended starting dose, without professional medical guidance. This can lead to inaccurate dosing, potentially ineffective treatment, or masking of important side effects that should be monitored by a clinician.

At TrimRx, our empathetic and trustworthy approach means we prioritize your safety and results. Our personalized programs always involve doctor consultations and a carefully managed titration schedule, ensuring that your body adapts comfortably and effectively. We work to provide the least amount of medication needed to support you in maintaining your best health. If you’re curious about a tailored approach to GLP-1 medications, we invite you to take our free assessment quiz to explore your options.

The Benefits of a Personalized, Medically Supervised Approach

The appeal of “microdosing” often stems from a desire for a gentler introduction to medication and fewer side effects. While this desire is valid, achieving it safely and effectively requires professional medical oversight. At TrimRx, we champion a personalized, medically supervised approach that inherently incorporates the principles of gradual dosing and individual tailoring, moving beyond the uncertainties of informal “microdosing.”

Minimizing Side Effects Through Thoughtful Titration

One of the most significant benefits of our medically supervised programs is the careful titration schedule. We understand that GLP-1 medications can present gastrointestinal side effects, and our clinicians work diligently to mitigate these from the outset.

Gradual Dose Adjustment

Rather than jumping directly to a high dose, our programs begin with a low starting dose, such as the initial 0.25 mg for semaglutide. This allows your body ample time to adjust to the medication’s effects. Our healthcare providers then gradually increase the dosage over several weeks, monitoring your response and making adjustments as needed. This “start low, go slow” philosophy helps prevent the sudden onset of severe side effects, making your journey more comfortable and sustainable. This is the essence of a controlled, medically sound “microdosing” strategy.

Individualized Response

Every body is unique. What works for one person may not be ideal for another. Our clinicians recognize this variability and tailor your treatment plan accordingly. If you experience persistent side effects at a certain dose, we can adjust your titration schedule or explore alternative solutions. This level of personalized care is a cornerstone of our brand personality – empathetic, supportive, and results-oriented.

Optimizing Efficacy and Long-Term Results

Beyond managing side effects, a medically supervised approach ensures you are on the most effective dose to achieve your weight loss goals, safely and sustainably.

Finding the “Sweet Spot”

Clinical trials have established optimal dosing ranges for GLP-1 medications to achieve significant weight loss. While a very low dose might reduce side effects, it may not be sufficient to provide the full therapeutic benefits, such as significant appetite suppression, reduction in food noise, or improved metabolic markers. Our providers guide you to the “sweet spot”—the lowest effective dose that yields the desired results with minimal discomfort. This ensures you’re not under-dosing to the point of ineffectiveness, which is a key concern with unsupervised microdosing.

Sustained Weight Loss and Maintenance

GLP-1 medications are designed for long-term use, not just for short-term weight loss. Our programs focus on sustainable outcomes, including strategies for weight maintenance once you reach your goal. This might involve carefully adjusting your dose downwards to find the minimum effective amount needed to prevent weight regain – a truly personalized approach to long-term health. Our commitment is to help you avoid the frustrating cycle of weight regain, fostering lasting change.

Comprehensive Support and Safety

At TrimRx, our commitment to transparent service means providing a holistic approach that prioritizes your well-being.

Doctor Consultations and Lab Work

Every personalized program begins with thorough doctor consultations to assess your medical history and suitability for treatment. This includes essential lab work to ensure safety and to monitor your progress effectively. We work exclusively with FDA-registered and inspected pharmacies for the shipping of weight loss medications, ensuring the quality and integrity of your prescriptions. It is important to remember that while branded medications like Wegovy® are FDA-approved, compounded versions are not, although they are sourced from these regulated pharmacies to meet individual needs under clinical guidance.

Unlimited Support and No Hidden Fees

Your journey with TrimRx is backed by unlimited support from our care team. Whether you have questions about your medication, need advice on lifestyle adjustments, or require emotional support, we are here for you. We believe in transparency, which is why our comprehensive service includes doctor consultations, medication, lab work, unlimited support, and shipping with no hidden fees. Our approach remains consistent regardless of dosage changes, emphasizing continuity of care.

Addressing Specific Needs

For individuals with unique considerations, such as women experiencing perimenopausal weight gain, PCOS, or insulin resistance, a personalized, gentle titration can be particularly beneficial. It allows for metabolic rebalancing and hormonal support without overwhelming the system, aligning with our focus on root-cause healing and individualized care.

Choosing a medically supervised path, rather than attempting unsupervised microdosing, provides the expertise, safety, and comprehensive support necessary for a successful and sustainable weight loss journey. This trusted, innovative approach is what sets TrimRx apart. To learn more about how our personalized programs can benefit you, we encourage you to take our free assessment quiz today.

Navigating Prescription and Quick-Access Solutions with TrimRx

Understanding what is a micro dose of Wegovy is part of a broader conversation about how to effectively use weight loss tools. At TrimRx, we offer a range of solutions tailored to different needs, from prescription medications requiring a personalized assessment to quick-access supplements that support your overall wellness journey. Our goal is to provide safe, effective, and individualized care, combining advanced medical science with modern technology.

Personalized Weight Loss Program: Prescription Medications

Our prescription weight loss programs are designed for individuals seeking significant, medically supervised weight loss. These programs utilize powerful GLP-1 medications that require a thorough medical evaluation to ensure eligibility and safety.

Our Medication Offerings:

  • Compounded Semaglutide: An injectable form of semaglutide, provided through FDA-registered, inspected, and approved pharmacies. Please note that compounded medications are not FDA-approved.
  • Oral Semaglutide: An oral form of semaglutide, also dispensed by our partner pharmacies.
  • Ozempic®: A branded, FDA-approved injectable semaglutide medication primarily for type 2 diabetes but used off-label for weight loss.
  • Compounded Tirzepatide: An injectable form of tirzepatide, provided through FDA-registered, inspected, and approved pharmacies. Compounded medications are not FDA-approved.
  • Oral Tirzepatide: An oral form of tirzepatide, dispensed by our partner pharmacies.
  • Mounjaro®: A branded, FDA-approved injectable tirzepatide medication primarily for type 2 diabetes but used off-label for weight loss.
  • Zepbound®: A branded, FDA-approved injectable tirzepatide medication specifically for weight loss.
  • Wegovy®: A branded, FDA-approved injectable semaglutide medication specifically for weight loss.

For any of these prescription medications, the first step is always to complete our free assessment quiz. This comprehensive evaluation helps our medical team determine your eligibility and craft a personalized treatment plan that aligns with your health profile and weight loss goals. This assessment is crucial for ensuring that you receive the safest and most effective medication and dosing strategy, moving beyond speculative “microdosing” to a truly medically sound approach. Our commitment is to transparent service, encompassing doctor consultations, medication, lab work, unlimited support, and shipping with no hidden fees, with our approach remaining consistent regardless of dosage changes.

Quick-Access Supplements: Immediate Support for Your Journey

Beyond prescription medications, we understand that many individuals are looking for accessible support to enhance their weight loss and wellness efforts. Our quick-access supplements are formulated to complement a healthy lifestyle and are available for immediate purchase, without the need for a quiz.

GLP-1 Daily Support

Our GLP-1 Daily Support supplement is designed to provide comprehensive metabolic support. It contains a blend of ingredients aimed at enhancing natural GLP-1 production, supporting healthy blood sugar levels, and managing appetite. This can be an excellent option for those looking for natural ways to feel fuller and reduce cravings, whether they are on a prescription GLP-1 medication or simply seeking general wellness support. It’s an ideal way to proactively support your body’s natural metabolic functions.

Weight Loss Boost

The Weight Loss Boost supplement is crafted to give your metabolism an extra push. It features ingredients known to support fat metabolism, increase energy levels, and aid in overall weight management. This supplement can be particularly beneficial for individuals looking to maximize their efforts in conjunction with diet and exercise, helping to break through plateaus and energize their journey.

These quick-access supplements exemplify our brand’s dedication to providing versatile and effective tools for healthier living. They offer an immediate way to engage with your health goals, providing foundational support that can be integrated into almost any wellness regimen.

Whether you’re exploring the transformative potential of prescription GLP-1s through a personalized plan or seeking daily support with our targeted supplements, TrimRx is here to empower your journey. Our innovative and supportive approach ensures that you have access to solutions that are right for you, guided by science and empathy every step of the way. We aim to be your trusted partner in achieving sustainable weight loss and embracing a healthier lifestyle.

The Importance of Professional Medical Guidance

In the world of weight loss, where conflicting information and quick fixes abound, the role of professional medical guidance cannot be overstated. This is particularly true when discussing potent medications like GLP-1 receptor agonists and concepts such as what is a micro dose of Wegovy. Relying on anecdotal advice or attempting self-dosing without proper oversight carries significant risks that can undermine both your health and your progress.

Risks of Unsupervised Dosing

While the internet and social media are rife with discussions about “microdosing” GLP-1s, it is imperative to understand the inherent dangers of such practices without clinical supervision.

Inaccurate Dosing and Potential Ineffectiveness

Medication pens for GLP-1s are precisely calibrated for specific doses. Attempting to “microdose” by counting clicks or modifying the device can lead to highly inaccurate dosages. If the dose is too low, the medication may simply be ineffective, leading to frustration and wasted effort. Conversely, even small deviations can lead to unexpected side effects. Clinical trials meticulously determine the safest and most effective doses, and these established titration schedules are evidence-based. Unsupervised deviations from these protocols mean you are essentially experimenting with your health.

Unmanaged Side Effects and Complications

GLP-1 medications, while generally well-tolerated when administered correctly, can cause side effects. These include not only common gastrointestinal issues but also potentially serious complications such as pancreatitis, gallbladder problems, increased heart rate, or kidney issues due to dehydration. Without medical monitoring, these side effects might go unnoticed, mismanaged, or worsen, posing significant health risks. A healthcare provider can not only advise on managing common side effects but also screen for contraindications and monitor for rarer, more serious adverse events.

Supply and Storage Concerns

Unsupervised microdosing might involve attempting to extend the life of medication pens beyond their recommended usage period or storing them improperly. These practices can compromise the medication’s stability, sterility, and effectiveness, potentially leading to infections or reduced therapeutic action. Manufacturers explicitly state that pens are designed for single-use, fixed doses, and splitting doses can increase the risk of contamination.

The TrimRx Advantage: Safety, Trust, and Expertise

At TrimRx, our entire framework is built upon providing a safe, trustworthy, and expert-guided weight loss journey. We understand the allure of seeking shortcuts or ways to minimize discomfort, but we firmly believe that true success comes from a structured, medically sound approach.

Personalized Care from Qualified Clinicians

Our process begins with a comprehensive assessment through our free assessment quiz, followed by consultations with licensed healthcare providers. These professionals conduct thorough evaluations, review your medical history, and consider any existing conditions to determine the most appropriate treatment plan for you. They understand the nuances of GLP-1 medications, including the approved dosing schedules and how to adjust them for optimal patient outcomes within safe, established parameters.

Adherence to Medical Guidelines

We adhere strictly to medical guidelines for prescribing and monitoring GLP-1 medications. Our clinicians manage the titration process carefully, ensuring that any dose adjustments are made safely and scientifically, always prioritizing your health and well-being. This includes providing the least amount of medication needed to support you in maintaining your best health, akin to a medically managed “microdosing” for maintenance, but always within professional oversight.

High-Quality, Authentic Medications

TrimRx partners exclusively with FDA-registered and inspected pharmacies to dispense all prescription medications, including branded options like Wegovy® and Zepbound®, and compounded alternatives. This ensures that you receive authentic, high-quality medication that meets rigorous safety standards. We clearly differentiate that while branded medications are FDA-approved, compounded medications are not, but they are sourced from regulated facilities. This commitment to quality is fundamental to our brand’s innovative and trustworthy identity.

Ongoing Support and Monitoring

Your journey with TrimRx doesn’t end after your prescription. We provide unlimited support to address any questions or concerns that arise. Our team continuously monitors your progress and helps manage any side effects, ensuring you feel supported every step of the way. This continuous engagement helps build sustainable habits and ensures the long-term success of your weight loss efforts.

Embarking on a weight loss journey with powerful medications requires careful consideration and professional partnership. By choosing TrimRx, you gain access to compassionate care, advanced medical science, and a transparent approach that respects your unique journey. We encourage you to take our free assessment quiz to begin a safe, effective, and truly personalized path to a healthier you.

Conclusion: Embracing a Personalized Path to Sustainable Weight Loss

The conversation around what is a micro dose of Wegovy highlights a universal desire: to achieve effective weight loss with minimal discomfort and maximum safety. While the informal concept of “microdosing” has gained attention, the critical takeaway is the paramount importance of a personalized, medically supervised approach. This method, which inherently incorporates gradual dose titration, is the safest and most effective way to harness the power of GLP-1 medications like Wegovy® for sustainable weight management.

At TrimRx, our foundation is built on merging cutting-edge telehealth innovations with effective weight loss solutions, offering a user-friendly and supportive platform for individuals. We believe that sustainable weight loss is achieved through science, empathy, and a transparent approach, not through unsupported experimentation. Our programs are designed to provide compassionate care that respects every individual’s unique journey, combining advanced medical science with modern technology.

When you embark on a personalized weight loss program with TrimRx, you are choosing a path that prioritizes your health and long-term success. From the initial comprehensive doctor consultations and essential lab work to the carefully managed medication titration and unlimited ongoing support, every aspect of our service is designed with your well-being in mind. We partner with FDA-registered and inspected pharmacies to ensure the highest quality of medications, whether they are FDA-approved branded options like Wegovy®, Zepbound®, Ozempic®, and Mounjaro®, or expertly compounded alternatives. Our transparent approach means you can trust that there are no hidden fees—just comprehensive care and unwavering support.

Beyond prescription medications, we also offer quick-access supplements like GLP-1 Daily Support and Weight Loss Boost to further empower your wellness journey. These offerings underscore our commitment to providing a diverse toolkit for individuals aged 18 to 74 who are navigating the complexities of weight management.

Ultimately, achieving sustainable weight loss is a journey, not a destination, and it’s one best undertaken with expert guidance. If you’ve been grappling with weight-related challenges or feel overwhelmed by constant food noise, we invite you to take the first step towards a more empowered and healthier future. Discover how a personalized plan can transform your approach to weight management by taking our free assessment quiz today. Let TrimRx be your trusted partner in unlocking your potential for lasting health and well-being.

Frequently Asked Questions (FAQ)

What is the medically recommended starting dose for Wegovy®?

The medically recommended starting dose for Wegovy® is 0.25 mg once per week. This low dose is then gradually increased over several weeks, under medical supervision, to allow your body to adjust to the medication and minimize potential side effects. The typical maintenance dose for Wegovy® is 2.4 mg once weekly, but individual titration plans vary based on response and tolerability.

Is “microdosing” Wegovy® safe or effective?

Unsupervised “microdosing” of Wegovy® (taking doses lower than recommended without medical guidance) is not recommended. There is currently no robust clinical evidence to support its safety or effectiveness for weight loss. While the intention might be to reduce side effects, it can lead to inaccurate dosing, potentially ineffective treatment, unmanaged side effects, and risks related to medication integrity. TrimRx emphasizes a medically supervised approach where initial low doses and gradual titration are carefully managed by healthcare providers for both safety and efficacy.

How does TrimRx ensure a personalized approach to medication dosing?

At TrimRx, our personalized approach begins with a free assessment quiz and thorough doctor consultations. Our licensed clinicians evaluate your medical history, health goals, and individual response to medication. Based on this, they develop a tailored treatment plan that includes a carefully managed titration schedule, starting with the lowest effective dose and gradually increasing as tolerated. This ensures your body adjusts comfortably and you achieve optimal results with minimal side effects, reflecting our empathetic and supportive care.

Can I get support for my weight loss journey even if I’m not on prescription medication?

Absolutely! TrimRx offers quick-access supplements that can support your overall wellness and weight management goals without requiring a prescription or quiz. Our GLP-1 Daily Support helps enhance natural GLP-1 production and manage appetite, while our Weight Loss Boost aids metabolism and energy. These are available for immediate purchase to complement a healthy lifestyle and provide foundational support for your journey.

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