Trulicity Cost at Costco in 2026: Real Pricing Breakdown

Introduction

Trulicity® (dulaglutide) is Eli Lilly’s once-weekly GLP-1 injection, FDA-approved in 2014 for type 2 diabetes and approved in 2020 for cardiovascular risk reduction in adults with type 2 diabetes. Lilly’s wholesale acquisition cost sits near $987 per 4-pen monthly carton, and Costco’s pharmacy is consistently among the cheapest U.S. cash options for the drug in 2026.

Costco’s 2026 cash price for a 4-pen Trulicity carton runs $890 to $980, with the typical receipt around $928. Costco sits at the bottom of national chain pricing on Trulicity, edging out Walmart and Sam’s Club by $10 to $50 per fill depending on market.

Here’s what Costco really charges, how non-members can use the pharmacy, and how the manufacturer card and coupons compare.

At TrimRx, we believe that understanding your options is the first step toward a more manageable health journey. You can take the free assessment quiz if you’re ready to see whether a personalized program is a fit for you.

What Does Trulicity Cost at Costco in 2026?

A 4-pen Trulicity carton at Costco runs $890 to $980 cash in 2026 for any standard strength. The carton covers 28 days, so it’s the monthly cash burden for uninsured patients without a coupon.

Quick Answer: Costco’s cash price for a 4-pen Trulicity carton runs $890 to $980 in 2026

Costco’s pharmacy operates on slim margins because Costco’s business model is membership revenue, not script markup. That allows the pharmacy to set cash retail well below CVS, Walgreens, and Rite Aid, and a few dollars below Walmart on most days.

NDC 0002-1433-80 (0.75 mg) and NDC 0002-1434-80 (1.5 mg) are standard stock at Costco pharmacies.

How Does Costco Compare to Other Warehouses and Chain Pharmacies?

Costco’s national average for Trulicity is $928 in a Q1 2026 GoodRx scan. Sam’s Club averaged $945, Walmart $980, Kroger $1,022, CVS $1,068, Walgreens $1,082, and Rite Aid $1,089.

So Costco is roughly $50 cheaper than Walmart, $140 cheaper than CVS, and $150 cheaper than Walgreens on cash retail. The savings compound over a 12-month treatment cycle. A patient filling Trulicity monthly at Costco saves $1,680 annually versus filling at Walgreens.

The trade-off is Costco’s smaller pharmacy footprint, fewer locations than Walmart or CVS, and warehouse access requirements for the storefront.

Can I Use Costco’s Pharmacy Without a Costco Membership?

Yes. Federal law (the Federal Trade Commission’s prescription drug provisions) requires Costco to allow any member of the public to use its pharmacy regardless of membership status. The Costco pharmacy is also exempt from members-only rules under most state pharmacy regulations.

To use the pharmacy as a non-member, tell the greeter at the warehouse entrance that you are going to the pharmacy. They will direct you in. Some Costco locations have separate pharmacy entrances that bypass the warehouse entirely.

The Costco Member Prescription Program (CMPP) is a perk for executive members and includes additional discounts on hundreds of generics, but the base pharmacy access is open to everyone.

Will the Trulicity Savings Card Work at Costco?

Yes. The Eli Lilly Trulicity Savings Card is accepted at every Costco pharmacy. Commercially insured patients with covered plans pay as little as $25 for a 1-month supply or $75 for a 3-month supply. Patients with commercial coverage that does not cover Trulicity get up to $150 off per month.

The card excludes Medicare, Medicaid, TRICARE, VA, and other government plan patients. Activation runs through trulicity.com and takes a few minutes.

Costco pharmacists run the savings card after insurance adjudication. If commercial PA fails, the card still works in the cash-pay path with the alternative tier discount.

Can GoodRx or SingleCare Beat Costco’s Cash Price?

GoodRx at Costco brings Trulicity to roughly $860 to $940 per 4-pen carton in 2026, a 3 to 7 percent cut off Costco’s already-low cash price. SingleCare runs within $20 of GoodRx most months. The Costco pharmacy will run whichever single coupon delivers the lowest out-the-door price.

The savings card almost always wins for commercial patients. GoodRx wins for uninsured and Medicare-eligible patients.

For uninsured patients, Costco cash with a GoodRx coupon at $870 to $940 is among the lowest legitimate U.S. prices for Trulicity in 2026.

Does Costco Insurance Billing Help If My Plan Covers Trulicity?

Commercial plans that cover Trulicity typically place it on a preferred or non-preferred specialty tier. Costco pharmacy copays run $30 to $100 a month after prior authorization, with coinsurance plans hitting 20 to 35 percent of the allowed cost.

Costco pharmacists handle prior auth submissions in-house and follow up with prescriber offices. Most PAs return within 48 to 72 hours for a drug with a clear clinical indication like type 2 diabetes.

Medicare Part D covers Trulicity for type 2 diabetes, so the 2026 Inflation Reduction Act $2,000 Part D out-of-pocket cap applies. Costco pharmacy accepts most Medicare Part D plans.

Key Takeaway: The Trulicity Savings Card from Eli Lilly drops eligible commercial patients to $25 a month

What About Costco Mail-order for Trulicity?

Costco Pharmacy Mail Service ships Trulicity in insulated cold packaging with two-day delivery. A 90-day Trulicity fill by mail typically matches the in-store per-month price, sometimes a few dollars lower.

Costco mail-order does not require a warehouse membership. The service is open to anyone with a valid prescription. Setup takes about 10 minutes online and the first fill arrives within 5 to 7 business days after prescription receipt.

For commercial patients using the Lilly savings card with a 3-month supply benefit, Costco mail-order is one of the most efficient and lowest-cost paths in U.S. retail pharmacy.

How Does Trulicity Compare to Newer GLP-1s Clinically?

Trulicity’s REWIND trial (Gerstein et al. 2019, Lancet) showed 12 percent reduction in major adverse cardiovascular events in adults with type 2 diabetes over 5.4 years. That gives Trulicity strong cardiovascular outcome evidence.

The SUSTAIN-6 trial (Marso et al. 2016, NEJM) showed weekly semaglutide reduced MACE by 26 percent in adults with type 2 diabetes. The SURPASS program established weekly tirzepatide as superior to semaglutide on glycemic control and weight loss in head-to-head data.

For diabetes alone, all three (Trulicity, Ozempic®, Mounjaro®) are clinically reasonable. The right choice depends on weight goals, side effect tolerance, and cost.

What’s the Cheapest Legitimate Way to Buy Trulicity in 2026?

For commercial patients, the Trulicity Savings Card at any participating pharmacy, including Costco, drops the price to $25 a month. That is the cheapest path.

For Medicare patients, the 2026 Part D $2,000 out-of-pocket cap is the main protection. Combined with Costco’s already-low cash retail, Medicare patients filling Trulicity at Costco typically pay among the lowest prices in the country.

For uninsured patients, Costco cash with a GoodRx coupon at $860 to $940 a month is the lowest major retail option in 2026. Sam’s Club is within $20. Walmart is within $50.

Are There Compounded GLP-1 Alternatives to Trulicity?

Yes. Compounded semaglutide and tirzepatide through licensed telehealth platforms became major GLP-1 alternatives in 2024 and 2025. The FDA removed semaglutide from the shortage list in February 2025 and tirzepatide in December 2024, tightening the compounding regulatory environment.

Pharmacies operating under USP 503A and 503B can still produce personalized compounded GLP-1 formulations for patients with valid prescriptions and demonstrated clinical need.

TrimRx connects patients with licensed prescribers and compounding pharmacies for personalized semaglutide and tirzepatide plans starting near $199 a month, including the medication, prescriber consult, and ongoing follow-up.

Bottom line: Compounded semaglutide and tirzepatide through telehealth platforms like TrimRx start near $199 a month

FAQ

Do I Need a Costco Membership to Fill Trulicity at the Pharmacy?

No. Federal law allows non-members to use Costco’s pharmacy. Tell the warehouse greeter you are going to the pharmacy and they will direct you in. Some Costco locations have separate pharmacy entrances.

Does Costco Stock All Trulicity Strengths?

Most Costco pharmacies stock 0.75 mg and 1.5 mg as standard inventory. The 3.0 mg and 4.5 mg titration doses are usually available with a day or two of advance notice. Costco’s smaller pharmacy footprint means inventory can be tighter than at CVS or Walgreens.

Can I Use the Costco Member Prescription Program (CMPP) on Trulicity?

CMPP discounts focus on generics. Trulicity is brand-only and patent-protected, so CMPP does not deliver meaningful additional savings on Trulicity specifically. The base Costco cash price plus the Lilly savings card or a GoodRx coupon is the cheapest path.

Does Costco Pharmacy Accept HSA and FSA Cards for Trulicity?

Yes. Trulicity is FSA and HSA eligible when prescribed for type 2 diabetes. The pharmacy will swipe the card for the patient responsibility portion.

What’s the Storage Requirement for Trulicity From Costco?

Trulicity pens require refrigeration at 36 to 46 degrees Fahrenheit before first use. After first use, each pen is stable at room temperature up to 86 degrees for 14 days. Costco dispenses with cold-pack handling instructions.

Can Costco Fill a 90-day Trulicity Prescription?

Yes. Costco pharmacy and Costco Mail Service both fill 90-day Trulicity supplies for plans that permit it. The 90-day fill is often the most efficient path for chronic Trulicity users.

Is Costco Pharmacy Open to Non-members for All Prescriptions?

Yes. The non-member pharmacy access rule applies to all prescriptions, not just specialty drugs. Patients can fill any legitimate prescription at Costco without a membership.

Disclaimer: This content is for informational purposes only and does not constitute medical advice. It is not intended to diagnose, treat, cure, or prevent any disease or condition. Individual results may vary. Always consult a qualified healthcare professional before starting any weight loss program or medication.