Are Chills a Side Effect of Wegovy?

Reading time
7 min
Published on
August 4, 2025
Updated on
November 18, 2025
Are Chills a Side Effect of Wegovy?

Introduction

Have you ever noticed an unexpected chill running through your body after starting a new medication? If you’ve recently begun taking Wegovy (semaglutide) for weight loss, you might be wondering if those chills are related to your treatment. In the world of weight-loss medications, Wegovy has gained attention for its ability to help individuals shed pounds effectively. However, as with any medication, understanding potential side effects is crucial.

In this blog post, we will delve into the topic of whether chills can be a side effect of Wegovy. We aim to provide you with a comprehensive understanding of this medication, its side effects, and how we at TrimRx can support you on your weight loss journey. By the end of this article, you will not only understand the connection between chills and Wegovy but also gain insights into managing any side effects you may experience.

Together, let’s explore the nuances of Wegovy, its side effects, and what you can expect during your weight loss journey.

Understanding Wegovy: What Is It?

Wegovy is a prescription medication approved by the FDA for weight management in adults with obesity or overweight individuals with weight-related health issues. This medication is administered as a once-weekly injection and works by mimicking the effects of a natural hormone called GLP-1 (glucagon-like peptide-1). By acting on the brain’s appetite regulation centers, Wegovy helps to reduce hunger and increase feelings of fullness, ultimately leading to weight loss.

Studies have shown that individuals using Wegovy can achieve significant weight loss when combined with a healthy diet and exercise program. However, as with any medication, it’s important to be aware of potential side effects, including the rare occurrence of chills.

Common Side Effects of Wegovy

When starting any new medication, it’s essential to understand the possible side effects. While Wegovy is generally well-tolerated, some individuals may experience side effects as their bodies adjust to the medication. Here are some common side effects associated with Wegovy:

  • Nausea: One of the most frequently reported side effects, occurring in about 44% of users, especially during the initial weeks of treatment.
  • Diarrhea: Approximately 30% of individuals might experience diarrhea, particularly when starting or adjusting doses.
  • Vomiting and Constipation: These effects can also occur but are generally temporary and resolve with time.
  • Stomach Pain and Bloating: Many users report discomfort in the abdominal area during the early stages.
  • Fatigue and Dizziness: Some individuals may feel more tired or lightheaded when starting Wegovy.

While chills are not commonly listed as a side effect of Wegovy, it’s essential to recognize how individual experiences can vary.

The Connection Between Chills and Wegovy

Feeling cold or experiencing chills while on Wegovy can be perplexing. Although chills are not a well-documented side effect of this medication, several physiological factors may contribute to this sensation as you undergo weight loss:

  1. Fat Loss and Thermoregulation: As you lose weight, particularly fat, your body’s insulation may decrease. Fat acts as a natural insulator, helping to retain body heat. A reduction in fat mass can lead to a greater sensitivity to temperature changes.
  2. Metabolic Changes: Weight loss medications, including Wegovy, can induce changes in metabolism. As your body adjusts to a new caloric intake and energy expenditure, it’s possible for the thermogenic response (heat production) to be affected, potentially creating sensations of chills.
  3. Eating Less: Wegovy works by suppressing appetite, leading to a lower overall caloric intake. This decrease in food consumption can result in less heat being generated through digestion, which might explain why some individuals feel colder.
  4. Muscle Mass Reduction: Rapid weight loss can sometimes lead to a decrease in muscle mass. Muscle tissue is metabolically active and generates heat. A reduction in muscle mass may contribute to feeling cooler.
  5. Hormonal Fluctuations: Wegovy affects hormones that regulate appetite and metabolism. Changes in hormone levels, particularly those related to the thyroid, can influence body temperature regulation.

It’s Important to Communicate

If you are experiencing chills or feeling unusually cold while on Wegovy, it’s crucial to communicate this with your healthcare provider. They can help you determine whether these sensations are related to the medication or if there may be other underlying causes.

Managing Side Effects

At TrimRx, we understand that embarking on a weight loss journey can come with challenges. While Wegovy can be an effective part of your weight loss strategy, managing side effects is equally important. Here are some tips to help you navigate any discomfort:

  • Stay Warm: If you feel chilly, dress in layers or use blankets to maintain body warmth.
  • Monitor Your Symptoms: Keep a journal of any side effects you experience, including chills, and share this information with your healthcare provider during your follow-up appointments.
  • Hydration and Nutrition: Ensure you are staying hydrated and consuming a balanced diet that supports your weight loss goals.
  • Regular Check-Ins: Engage in regular consultations with your healthcare team to discuss your progress and any side effects you may be experiencing.

Our Commitment to You

At TrimRx, we are dedicated to providing personalized care throughout your weight loss journey. Our approach combines advanced medical science with empathetic support to ensure your experience is as smooth as possible. We offer a free assessment quiz to help you determine eligibility for our prescription weight loss medications, including Wegovy. This personalized treatment plan ensures that your weight loss strategy aligns with your specific health needs.

Take our free assessment quiz today to explore whether Wegovy is right for you: Take the Assessment Quiz.

Additionally, we offer quick-access supplements like our GLP-1 Daily Support and Weight Loss Boost to support your overall wellness during your weight loss journey.

Conclusion

In summary, while chills are not a common side effect of Wegovy, they can occur due to various physiological changes associated with weight loss and the medication’s effects on metabolism. If you experience chills or any other unusual symptoms while taking Wegovy, it’s essential to consult your healthcare provider for guidance.

We at TrimRx are here to support you every step of the way, combining compassionate care with medically supervised weight loss solutions. Your journey toward a healthier you is important to us, and we are committed to helping you achieve your weight loss goals safely and effectively.

FAQ

Can chills be caused by losing weight on Wegovy?
Yes, as you lose weight, particularly fat, your body may become less insulated, leading to feelings of cold or chills.

What should I do if I experience chills while on Wegovy?
If you experience chills or any other unusual symptoms, it’s crucial to communicate with your healthcare provider for further evaluation.

Is Wegovy safe for long-term use?
Wegovy is approved for long-term use in those who achieve significant weight loss. Regular check-ins with your healthcare provider are essential to monitor your progress and manage any side effects.

How can I manage side effects while using Wegovy?
You can manage side effects by staying warm, monitoring your symptoms, maintaining proper hydration and nutrition, and consulting with your healthcare team regularly.

Can I take supplements while on Wegovy?
Yes, certain supplements can support your weight loss journey. Explore our GLP-1 Daily Support and Weight Loss Boost for additional support.

Your health is our priority, and we are here to help you every step of the way!

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