Longevity

5-Amino-1MQ is a small molecule that blocks an enzyme called NNMT in fat cells, which in mice raises NAD+ and reduces fat gain.

Introduction A well-designed 12-week GLP-1 program is built around the titration schedule, with the medication doing the appetite work while you build the habits…

Introduction SS-31, also called elamipretide, is a mitochondria-targeted peptide that concentrates inside the inner mitochondrial membrane and binds a lipid called cardiolipin. That single…

Introduction Vasoactive intestinal peptide, usually shortened to VIP, is a 28-amino-acid neuropeptide first isolated from porcine duodenum in 1970 by Sami Said and Viktor…

Introduction Thymosin alpha 1 is a 28-amino-acid peptide first isolated from calf thymus in 1972 by Allan Goldstein and colleagues at Albert Einstein College…

Introduction Thymalin is a polypeptide complex extracted from the thymus glands of calves, used in Russia and former Soviet states since the 1970s for…

The case for combining tesamorelin with semaglutide or tirzepatide rests on complementary mechanisms.

Tesamorelin works through a clean and well characterized mechanism.

Tesamorelin has the strongest evidence base of the peptides covered in this category.