Expired Mounjaro: Risks, Storage, and Safe Practices

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50 min
Published on
September 20, 2025
Updated on
September 20, 2025
Expired Mounjaro: Risks, Storage, and Safe Practices

Introduction

Imagine relying on a vital tool for your health, only to discover it might no longer be effective. This concern is particularly acute for individuals managing type 2 diabetes or embarking on a weight loss journey with medications like Mounjaro (tirzepatide). These advanced therapies represent a significant step forward in personalized health, but their efficacy hinges on proper use and storage. Just like any carefully crafted solution, Mounjaro has a specific shelf life, and disregarding this can have unintended consequences. The question of what happens if you take expired Mounjaro is not merely theoretical; it’s a practical consideration that impacts treatment outcomes, safety, and ultimately, your well-being.

In this comprehensive guide, we’ll delve into the intricacies of Mounjaro’s expiration, exploring the science behind medication stability, the potential risks of using a compromised dose, and the crucial role of correct storage. We will equip you with the knowledge to identify an expired or degraded pen and understand the necessary steps to take if you inadvertently use one. Beyond the technicalities, we’ll reinforce the profound importance of adhering to medication guidelines to ensure your treatment remains both safe and maximally effective. Our purpose is to demystify the topic, providing clarity and confidence in managing your health regimen. This post will cover everything from understanding expiration dates to optimal storage and disposal practices, all to empower you on your path to a healthier lifestyle.

Understanding Medication Expiration Dates

Every medication, including sophisticated treatments like Mounjaro, comes with an expiration date, a crucial piece of information that serves as the manufacturer’s promise of quality. This date isn’t arbitrary; it’s the culmination of rigorous scientific testing designed to determine how long a drug can maintain its full strength, purity, and safety under specified storage conditions. For those embracing a journey toward better health, comprehending this guarantee is fundamental to ensuring your treatment performs as intended.

The Manufacturer’s Guarantee

The expiration date printed on your Mounjaro pen and its packaging is more than just a timestamp; it’s the manufacturer’s assurance that, until this specific date, the medication will retain its complete potency and safety profile. This means the active ingredient, tirzepatide, is guaranteed to be present at the precise concentration needed to deliver its therapeutic effects, whether for managing blood sugar levels in type 2 diabetes or supporting significant weight loss. This stability is rigorously tested under controlled laboratory conditions, simulating various environmental factors to ensure consistent quality throughout the product’s designated shelf life. Once this date passes, the manufacturer can no longer guarantee that the medication will work as effectively or safely. It marks the point after which the chemical composition of the drug may begin to change, potentially leading to reduced efficacy or, in rare cases, altered safety. Therefore, adhering to this date is paramount for anyone relying on the medication for their health goals.

Beyond the Label: Factors Affecting Shelf Life

While the printed expiration date provides a general guideline, several real-world factors can significantly influence Mounjaro’s actual shelf life, sometimes causing it to expire prematurely. The printed date assumes ideal storage conditions. However, deviations from these conditions can accelerate the degradation of the active ingredient, tirzepatide. For instance, exposure to extreme temperatures—whether excessive heat or freezing—can chemically alter the medication, rendering it less effective or even unusable long before its official expiration date. Similarly, prolonged exposure to light, especially direct sunlight, can degrade the sensitive components within the medication.

Understanding these variables is crucial because a visually intact pen might still contain compromised medication if it hasn’t been stored correctly. This highlights why strict adherence to storage instructions, as we will explore further, is just as important as checking the expiration date itself. It’s a testament to our commitment at TrimRx that we not only provide access to these advanced solutions but also equip our community with the knowledge to maintain their integrity and ensure their full therapeutic benefit. Our personalized weight loss programs emphasize not just the medication itself, but also the comprehensive support and education needed for a truly effective and sustainable health journey.

What Happens If You Take Expired Mounjaro: The Core Risks

The prospect of what happens if you take expired Mounjaro is a serious concern for anyone managing their health with this medication. While it might be tempting to use a pen that has just passed its expiration date to avoid waste, the potential consequences underscore why such actions are not recommended. The primary risks revolve around the medication’s reduced effectiveness and, in certain circumstances, potential safety implications.

Reduced Effectiveness: The Primary Concern

The most significant risk associated with using expired Mounjaro is a noticeable reduction in its effectiveness. Over time, the active ingredient, tirzepatide, can chemically break down, leading to a loss of potency. This degradation means that the dose you inject may contain less active medication than intended, which can have direct and adverse effects on your treatment goals.

For individuals with type 2 diabetes, reduced potency can mean uncontrolled blood sugar levels. Mounjaro is FDA-approved to help manage blood sugar, and a diminished effect could lead to prolonged hyperglycemia, with symptoms such as increased thirst, frequent urination, and fatigue. Such fluctuations can undermine the stability of your glucose management, potentially requiring adjustments to your overall treatment plan.

Similarly, for those utilizing Mounjaro as part of a personalized weight loss program, an expired dose may significantly compromise the anticipated benefits. The mechanism of tirzepatide involves activating GLP-1 and GIP receptors, which helps reduce appetite, curb cravings, and promote feelings of fullness. If the medication is less potent, these crucial effects may be weakened, leading to slower or halted progress in weight loss. This can be disheartening and counterproductive to the dedicated efforts made in adopting healthier lifestyle changes. At TrimRx, we understand the profound impact that effective medication has on achieving these health milestones. Our programs are designed to provide consistent, potent medication, ensuring you receive the full benefits of your personalized plan. This includes transparent guidance on medication handling, a testament to our empathetic and results-oriented approach. To discover how our comprehensive service, including doctor consultations, medication, lab work, unlimited support, and shipping with no hidden fees, can support your journey, consider taking our free assessment quiz.

Potential Safety Implications

While the primary concern with expired Mounjaro is typically reduced efficacy rather than immediate danger, there are nuanced safety considerations worth understanding. The chemical degradation of tirzepatide means its composition might change in unpredictable ways. Although serious adverse reactions from expired medications are generally rare, the possibility of altered compounds cannot be entirely ruled out.

One aspect to consider is the impact on blood sugar stability for individuals with type 2 diabetes. If the expired medication fails to adequately control glucose levels, persistent hyperglycemia can lead to a cascade of negative health effects over time, including increased risk of complications. The goal of Mounjaro, which is FDA-approved, is to provide consistent control, and any deviation from this can be detrimental.

Furthermore, improper storage conditions that lead to premature expiration could also introduce other risks. For instance, if a pen has been exposed to extreme temperatures or otherwise compromised, the sterility of the solution could be affected, potentially increasing the risk of localized irritation or infection at the injection site. While such occurrences are not common, they highlight the importance of maintaining the integrity of the medication from manufacturing to administration.

Using ineffective medication also translates to delayed treatment progress. This can be frustrating and may necessitate a complete reassessment of your dosage or even a switch to alternative therapies sooner than anticipated. Our brand, TrimRx, is built on trust and safety, partnering exclusively with FDA-registered and inspected pharmacies to ensure the highest quality of medications like Mounjaro, Zepbound®, and Ozempic®. We prioritize your well-being by emphasizing the critical role of proper medication storage and usage within our personalized weight loss programs, ensuring you navigate your health journey with confidence and peace of mind. We are committed to transparent service, ensuring our approach remains consistent, focusing on your safety and results.

Identifying Compromised Mounjaro: Beyond the Date

Understanding what happens if you take expired Mounjaro extends beyond simply noting the date on the box. While the printed expiration date is your first line of defense, a medication can become compromised even before that date if it’s not stored correctly. Vigilance for both the official expiration and visual cues of degradation is essential for ensuring the integrity of your treatment.

Checking the Printed Expiration Date

The most straightforward and fundamental step in determining if your Mounjaro is still viable is to check the expiration date clearly printed on both the pen itself and its outer packaging. This date typically indicates the month and year until which the manufacturer guarantees the product’s full potency and safety when stored under recommended conditions. It’s a good practice to form a habit of checking this date every time you prepare a dose, and especially when you receive a new prescription from your pharmacy. This simple check ensures that you are consistently using the freshest and most effective supply available. If the date has passed, regardless of how the medication looks, it should not be used and must be safely discarded.

Visual and Physical Indicators of Degradation

While the expiration date is non-negotiable, Mounjaro can also show physical signs of degradation that indicate it has gone bad prematurely. The active ingredient, tirzepatide, is a sensitive compound, and its stability can be compromised by various environmental factors.

Always inspect your Mounjaro pen before use. The solution inside should be clear and colorless or slightly yellow. If you observe any of the following, do not use the pen:

  • Cloudiness or Discoloration: The solution should not appear cloudy, hazy, or significantly discolored. Any deviation from its clear or slightly yellow appearance suggests chemical changes have occurred.
  • Presence of Particles: Look for any floating particles, clumps, or precipitates within the solution. These indicate that the medication has broken down and is no longer stable or safe for injection.
  • Leaks or Damage to the Pen: Inspect the pen for any cracks, leaks, or damage to its integrity. A compromised pen could mean the medication has been exposed to air or contaminants, affecting its sterility and effectiveness.

These visual cues are critical indicators that the medication’s integrity has been compromised, even if the printed expiration date has not yet passed. When in doubt, it is always safer to err on the side of caution and not use the pen. At TrimRx, we empower you with the knowledge to make informed decisions about your medication, aligning with our commitment to compassionate care and personalized support throughout your weight loss journey.

Storage Conditions That Accelerate Expiration

Beyond the printed date and visible signs, improper storage conditions are a primary culprit behind Mounjaro’s premature expiration. The stability of tirzepatide, the active compound in Mounjaro, is highly sensitive to environmental factors, and deviating from recommended storage can quickly render the medication ineffective.

Crucially, Mounjaro must be stored correctly to maintain its effectiveness. While unopened pens are typically stored in the refrigerator, they can be kept unrefrigerated at room temperature (below 30°C or 86°F) for a limited time—specifically, up to 21 days. If a pen has been left out of refrigeration for longer than this period, it is considered compromised and should not be used, regardless of the printed expiration date. This applies even if it appears visually normal. Once removed from the refrigerator and kept at room temperature, it should never be returned to the fridge.

Exposure to excessive heat is another major threat. Temperatures above 30°C (86°F), such as those found in a hot car or direct sunlight, can rapidly degrade the medication. Similarly, accidental freezing is catastrophic for Mounjaro. If the medication has frozen, even if it subsequently thaws, its molecular structure is irreversibly damaged, and it must be discarded immediately. These extreme temperature exposures can cause the active ingredients to break down, leading to a loss of potency that cannot be reversed.

Understanding these critical storage requirements is not just about extending shelf life; it’s about preserving the therapeutic efficacy and safety of your medication. TrimRx emphasizes these best practices within our personalized programs, ensuring that every step of your weight loss journey is supported by trustworthy and effective solutions. Our medically supervised care focuses on providing all the necessary information, from proper medication handling to comprehensive support, helping you embrace healthier lifestyles with confidence.

Proper Storage: Safeguarding Your Mounjaro’s Efficacy

The power of Mounjaro in supporting blood sugar management and weight loss is undeniable, yet its effectiveness is intrinsically linked to how it is stored. Prioritizing proper storage isn’t just a recommendation; it’s a critical step in safeguarding the medication’s potency and ensuring you receive the full therapeutic benefit from every dose. Understanding and adhering to these guidelines prevents premature degradation and secures the integrity of your treatment.

Refrigeration: The Gold Standard

For Mounjaro, the preferred and most effective storage method before its initial use is refrigeration. Unopened Mounjaro pens should always be kept in a refrigerator at a temperature between 2°C and 8°C (36°F and 46°F). This cool environment is ideal for maintaining the stability of tirzepatide, the active ingredient, for its full intended shelf life, which typically extends up to the printed expiration date.

The reason for this precise temperature range lies in the nature of GLP-1 and GIP receptor agonists. These peptide-based medications are temperature-sensitive, meaning their delicate molecular structure can be compromised by warmer temperatures, leading to degradation. Storing Mounjaro in its original carton while refrigerated is also important, as this protects the medication from light exposure, which can further impact its stability.

Always ensure your refrigerator’s temperature is consistent and avoid placing pens near the back of the fridge or in freezer compartments, where temperatures can fluctuate or drop low enough to cause freezing. By consistently following these refrigeration guidelines, you uphold the manufacturer’s guarantee of potency and ensure your Mounjaro is ready to deliver its full benefits when you need it. This meticulous attention to detail is a hallmark of the comprehensive care we champion at TrimRx, reflecting our commitment to providing effective and safe weight loss solutions.

Room Temperature Guidelines

While refrigeration is the optimal storage condition for unopened Mounjaro pens, there are specific circumstances where storage at room temperature is permissible for a limited duration. This flexibility is particularly useful for daily convenience or during travel.

Mounjaro pens can be kept out of the refrigerator at room temperature, provided the temperature does not exceed 30°C (86°F). However, this period is strictly limited to a maximum of 21 days. It is crucial to mark the date you remove the pen from refrigeration to accurately track this 21-day window. Once a pen has been stored at room temperature for this duration, it must be used or safely discarded, even if the printed expiration date has not yet passed.

A critical rule to remember: do not return Mounjaro to the refrigerator once it has been stored at room temperature. Fluctuations between cold and room temperatures can be more detrimental to the medication’s stability than consistent room temperature storage within the allowed timeframe. Keeping the pen in its original carton, even at room temperature, continues to protect it from light. Adhering to these guidelines ensures that even when refrigerated storage isn’t continuous, the medication retains its efficacy for its intended use within the prescribed period, supporting your journey towards sustainable weight loss with confidence.

The Danger of Freezing

Among all improper storage conditions, freezing is arguably the most damaging and irreversible for Mounjaro. Unlike some other medications, Mounjaro must never be frozen. If a Mounjaro pen accidentally freezes, it must be discarded immediately, even if it thaws afterward.

The reason for this strict instruction is due to the delicate nature of the tirzepatide solution. Freezing can cause the active ingredients and other components of the liquid solution to denature or break down at a molecular level. This process can alter the medication’s chemical structure, leading to a complete loss of potency and potentially making it unsafe for use. Even if the solution appears normal after thawing, the damage has already occurred, rendering the medication ineffective and unreliable.

To prevent accidental freezing, it’s essential to store Mounjaro away from the freezer compartment within your refrigerator. Avoid placing pens directly against the back wall of the fridge, as these areas often have lower temperatures that can dip below freezing. This seemingly small detail in storage can have a profound impact on your treatment’s efficacy. At TrimRx, we believe in empowering our community with thorough knowledge, making sure every aspect of your personalized weight loss program, from medication access to storage guidance, supports your success. Our medically supervised weight loss solutions are designed for safety and effectiveness, and proper medication handling is a cornerstone of this commitment.

If You Accidentally Use Expired Mounjaro: Next Steps

Despite best intentions, sometimes an expired Mounjaro pen might be used inadvertently. Discovering you’ve taken a dose past its prime can be unsettling, but it’s important to approach the situation calmly and methodically. Understanding the appropriate steps to take can help mitigate potential issues and ensure your continued safety and progress.

Don’t Panic: Assessing the Situation

If you’ve accidentally injected an expired dose of Mounjaro, the first and most crucial step is to remain calm. It’s important to understand that in most cases, using expired Mounjaro is unlikely to cause immediate, severe harm. The primary concern, as previously discussed, is typically a reduction in its effectiveness.

However, the lack of full potency could mean your body hasn’t received the intended therapeutic effect. If you are using Mounjaro for type 2 diabetes, closely monitor your blood sugar levels. Keep a diligent log of your readings and any symptoms you might experience, such as unusual fatigue, increased thirst, or changes in appetite. For those on a weight loss journey, observe if your appetite suppression or feelings of fullness are less pronounced than usual.

It’s vital not to panic and immediately attempt to compensate by injecting another dose. The exact potency of the expired dose is unknown, and administering an additional amount could potentially lead to an overdose of tirzepatide, which can have its own set of adverse effects. Gather all relevant information, including the expiration date on the pen and any details about its storage history. This information will be valuable when you consult with a healthcare professional.

Consulting Your Healthcare Provider

Following an accidental injection of expired Mounjaro, the most responsible and recommended course of action is to promptly contact your healthcare provider or pharmacist. They are best equipped to provide personalized medical advice based on your individual health profile, the specific circumstances of the expired dose, and your ongoing treatment plan.

When you contact them, be prepared to share:

  • The exact expiration date on the pen.
  • How long ago you believe the medication expired.
  • How the pen was stored (e.g., refrigerated, at room temperature, exposed to heat).
  • Any symptoms you are experiencing, particularly if you are diabetic and noticing blood sugar fluctuations.
  • Your next scheduled dose.

Your provider will advise you on whether any adjustments to your monitoring routine are necessary, whether to continue with your next scheduled dose, or if a new prescription is required. They can assess the risk of reduced effectiveness and help ensure your treatment remains on track. Our platform at TrimRx ensures that you have access to medically supervised care and unlimited support, making it easy to consult with experts who understand your unique journey and can guide you through any unexpected situations with compassion and expertise. This personalized approach is foundational to our commitment to safe and effective weight loss.

Proper Disposal of Compromised Medication

Proper disposal of any expired or compromised medication, including Mounjaro, is not just a matter of convenience; it’s a crucial step for public safety and environmental protection. Once you have identified an expired or otherwise compromised Mounjaro pen, it should not be simply thrown into household trash without proper precautions.

Mounjaro pens are considered sharps because they contain a needle. All sharps, including used or expired Mounjaro pens, should be disposed of in an FDA-approved sharps disposal container immediately after use or once identified as compromised. These containers are specifically designed to safely store needles and prevent accidental punctures, which can spread infections or harm others. You can typically purchase sharps containers at pharmacies, medical supply stores, or online. In some areas, free sharps containers or disposal programs may be available through local doctors’ offices, hospitals, or health departments.

If an FDA-approved sharps container is not immediately available, a heavy-duty plastic household container, such as a laundry detergent bottle or bleach bottle, with a tight-fitting, puncture-resistant lid, can serve as a temporary alternative. Make sure to label it clearly as “sharps” and keep it out of reach of children and pets. Never dispose of sharps in recycling bins, toilets, or general trash bags. Once your sharps container is full, follow your community’s guidelines for proper disposal, which may include mail-back programs, supervised collection sites, or household hazardous waste disposal events. Our commitment to transparent and safe practices extends to providing guidance on all aspects of your medication use, reinforcing our dedication to your well-being and responsible health management.

Our Commitment to Your Safe and Effective Weight Loss Journey

At TrimRx, we understand that embarking on a weight loss journey is a deeply personal and often challenging endeavor. Our entire philosophy is built around supporting you with solutions that are not only clinically proven but also delivered with empathy, transparency, and a steadfast commitment to your safety and long-term success. The insights shared about what happens if you take expired Mounjaro underscore our dedication to equipping you with comprehensive knowledge, ensuring every aspect of your treatment is managed with informed care.

TrimRx: Merging Innovation with Compassionate Care

Our journey at TrimRx began with a shared vision to help individuals embrace healthier lifestyles by merging cutting-edge telehealth innovations with effective weight loss solutions. We recognized the need for a more accessible, personalized, and supportive approach to weight management, one that moves beyond one-size-fits-all methods. Our platform is a user-friendly and supportive space where individuals receive personalized, medically supervised care—all designed to make sustainable weight loss attainable and tailored to the individual. We believe that sustainable weight loss should be achieved through science, empathy, and a transparent approach. This means combining the latest advancements in medical science with modern technology, delivered with compassionate care that respects every individual’s unique journey. Our brand is empathetic, innovative, trustworthy, supportive, results-oriented, and personalized, ensuring you feel understood and empowered every step of the way.

Ensuring Quality and Trust in Your Medication

The integrity of your medication is paramount to your health outcomes, and at TrimRx, we leave no stone unturned in ensuring the highest standards of quality and trust. We emphasize that our medications, including Compounded Semaglutide, Oral Semaglutide, Ozempic®, Compounded Tirzepatide, Oral Tirzepatide, Mounjaro®, Zepbound®, and Wegovy®, are provided through FDA-registered, inspected, and approved pharmacies. This partnership guarantees that your medication is handled and dispensed with the utmost care and adherence to strict pharmaceutical guidelines. For branded medications like Ozempic®, Mounjaro®, Zepbound®, and Wegovy®, we proudly acknowledge their FDA approval, offering you an extra layer of confidence in their efficacy and safety.

Our commitment extends beyond providing access to these powerful tools. We offer a comprehensive service that includes doctor consultations, essential lab work, the medication itself, unlimited support from our dedicated team, and convenient shipping—all with no hidden fees. This transparent approach ensures that you understand every aspect of your personalized weight loss program. We are unwavering in our focus on safety, including clear guidance on proper medication storage and handling, like those discussed for Mounjaro. This commitment ensures that your journey with us is built on a foundation of reliability and trust, fostering results you can truly feel and see.

Your Personalized Path with TrimRx

Embarking on a weight loss journey is a significant step, and at TrimRx, we are here to walk alongside you, offering solutions tailored to your unique needs and health profile. We understand that effective weight management requires a personalized approach, and our offerings are designed to provide just that.

For those seeking the transformative benefits of prescription weight loss medications, we encourage you to take our free assessment quiz. This quick and easy quiz helps determine your eligibility for our personalized treatment plans, which may include options like Compounded Semaglutide, Oral Semaglutide, Ozempic®, Compounded Tirzepatide, Oral Tirzepatide, Mounjaro®, Zepbound®, or Wegovy®. Our medical team reviews your assessment to craft a program that aligns with your health goals and lifestyle, ensuring you receive medically supervised care that is both safe and effective.

We also recognize that some individuals may benefit from immediate support for their overall wellness during their weight loss journey. For those moments, we offer quick-access supplements that do not require a quiz for purchase. Our GLP-1 Daily Support is formulated to complement your wellness efforts, while our Weight Loss Boost offers additional assistance for your metabolic health. These supplements are readily available to support you, embodying our belief in comprehensive care that addresses various aspects of your health. With TrimRx, you gain a partner dedicated to making your weight loss goals not just achievable, but sustainable, through science, empathy, and unparalleled support.

Conclusion

Navigating the nuances of medication management, particularly concerning questions like what happens if you take expired Mounjaro, is a crucial aspect of any effective health journey. We’ve explored the vital role of expiration dates, the potential for reduced efficacy and nuanced safety considerations, and the critical importance of proper storage techniques—from refrigeration to avoiding freezing. Every step, from checking the label to understanding visual cues of degradation, plays a part in ensuring your medication delivers its full therapeutic promise.

Ultimately, your commitment to your health deserves solutions that are safe, effective, and reliable. At TrimRx, our unwavering dedication to your well-being drives every aspect of our personalized weight loss programs. We merge innovative telehealth with medically supervised care, ensuring you have access to high-quality medications from FDA-registered pharmacies, comprehensive support, and transparent guidance. We empower you with the knowledge and resources to make informed decisions, fostering sustainable habits and lasting results.

Prioritizing the integrity of your medication is an investment in your success. Should you have questions about your specific medication or wish to explore a personalized weight loss plan designed for your unique needs, we invite you to connect with our supportive team. Take the next step toward a healthier, more confident you by considering our free assessment quiz or exploring our immediate support supplements like GLP-1 Daily Support and Weight Loss Boost. Together, we can build a path to lasting health and vitality, grounded in science, empathy, and trust.

Frequently Asked Questions

Is it really dangerous to use Mounjaro after its expiration date?

While generally not immediately dangerous, the primary risk of using expired Mounjaro is a significant reduction in its effectiveness. The active ingredient, tirzepatide, can degrade over time, meaning the medication may not provide the full benefits for blood sugar management or weight loss. This reduced potency can lead to uncontrolled blood sugar levels for individuals with type 2 diabetes or a slower progression towards weight loss goals, which can be detrimental to your overall treatment plan.

How can I tell if my Mounjaro pen has expired prematurely?

Beyond the printed expiration date on the pen and packaging, Mounjaro can expire prematurely due to improper storage. Look for visual signs such as the solution appearing cloudy, discolored, or having visible particles floating in it. The pen should also be discarded if it has been unrefrigerated for more than 21 days, exposed to temperatures above 30°C (86°F), or if it has accidentally frozen. Any leaks or damage to the pen itself are also indicators that it should not be used.

What should I do if I accidentally inject expired Mounjaro?

If you’ve inadvertently used an expired Mounjaro dose, the first step is to remain calm. It’s unlikely to cause immediate severe harm, but you should monitor your symptoms closely. If you use Mounjaro for type 2 diabetes, pay extra attention to your blood sugar levels. Most importantly, contact your healthcare provider or pharmacist promptly. Do not inject another dose without their guidance, as this could lead to unintended consequences. Your provider can advise on next steps, monitoring, or whether a new prescription is needed.

What are the correct storage conditions to ensure my Mounjaro remains effective?

To maintain Mounjaro’s effectiveness, store unopened pens in a refrigerator between 2°C and 8°C (36°F and 46°F) in their original carton to protect them from light. Mounjaro must never be frozen; if it freezes, it must be discarded immediately. If needed, a pen can be kept at room temperature (below 30°C or 86°F) for up to 21 days, but once it has been out of the refrigerator for this period, or if the 21-day window passes, it must be used or discarded—never return it to the refrigerator. Adhering to these guidelines ensures your medication maintains its potency and safety.

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