Navigating Constipation on Semaglutide: Can You Take a Laxative for Relief?

Introduction

Embarking on a weight loss journey often brings a sense of renewed hope and determination, especially when supported by innovative medical advancements. Many individuals discover significant progress with medications like semaglutide and tirzepatide, which have emerged as powerful tools in metabolic health management. Yet, even with these transformative solutions, unexpected challenges can arise. One common, and often uncomfortable, side effect reported by individuals on these medications is constipation. This digestive discomfort can sometimes feel like an unwelcome detour on the path to improved well-being, raising questions about how to effectively manage it without compromising the broader health goals.

The experience of constipation—characterized by infrequent bowel movements, difficulty passing stool, or a feeling of incomplete evacuation—is more than just a minor inconvenience. It can impact daily comfort, energy levels, and overall quality of life, potentially leading some to question the sustainability of their treatment plan. Given the efficacy of GLP-1 receptor agonists like semaglutide and GIP/GLP-1 receptor co-agonists like tirzepatide in promoting satiety and aiding weight loss, understanding how to mitigate their associated side effects is paramount. This is where the topic of laxatives frequently comes into play. Individuals often wonder, “can I take a laxative while on semaglutide?” or similar GLP-1 medications, seeking clarity and safe solutions.

At TrimRx, our journey began with a shared vision to help individuals embrace healthier lifestyles by merging cutting-edge telehealth innovations with effective weight loss solutions. We understand that sustainable weight loss should be achieved through science, empathy, and a transparent approach. Our platform is a user-friendly and supportive space where individuals receive personalized, medically supervised care—all designed to make sustainable weight loss attainable and tailored to the individual. This commitment extends to providing comprehensive information and support for managing common side effects, ensuring your journey is as smooth and comfortable as possible.

This in-depth blog post aims to shed light on the connection between GLP-1 medications and constipation, exploring why it occurs and, crucially, addressing whether laxatives offer a safe and effective remedy. We will delve into the various types of laxatives, their mechanisms, and the essential lifestyle adjustments that complement their use. Furthermore, we will highlight when it is appropriate to seek professional medical guidance and how a personalized, comprehensive approach can make all the difference. By the end of this article, you will have a clearer understanding of how to proactively manage digestive discomfort, empowering you to maintain momentum on your transformative health journey. We’ll guide you through practical strategies, ensuring you have the knowledge and resources to navigate this common challenge effectively.

The Transformative Power of GLP-1s and the Challenge of Constipation

The landscape of weight management has been significantly reshaped by the introduction of glucagon-like peptide-1 (GLP-1) receptor agonists and glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide (GIP/GLP-1) receptor co-agonists. These medications represent a scientific breakthrough, offering substantial benefits for individuals striving to achieve a healthier weight and improve metabolic health. However, as with any potent medication, understanding their full impact—including potential side effects—is crucial for a successful and comfortable journey.

Understanding Semaglutide and Tirzepatide in Weight Management

At the heart of these innovative treatments are active ingredients like semaglutide and tirzepatide. Semaglutide, available through TrimRx as Compounded Semaglutide, Oral Semaglutide, and branded options like Ozempic® and Wegovy®, acts by mimicking a natural hormone called GLP-1 that our bodies release in response to eating. This mimicry leads to several beneficial effects for weight management and blood sugar control. Similarly, tirzepatide, offered by TrimRx as Compounded Tirzepatide, Oral Tirzepatide, and branded options such as Mounjaro® and Zepbound®, takes this a step further by mimicking both GLP-1 and GIP hormones, providing an even broader impact on metabolic pathways.

These medications primarily work through several key mechanisms:

• Appetite Regulation: They signal the brain to reduce appetite and increase feelings of fullness, leading to decreased calorie intake.
• Blood Sugar Control: For individuals with type 2 diabetes, they help regulate blood sugar levels by stimulating insulin release and reducing glucose production by the liver.
• Delayed Gastric Emptying: Perhaps most relevant to our discussion, these medications slow down the rate at which food leaves the stomach and moves into the small intestine. This prolongs the feeling of satiety, helping to manage hunger more effectively.

The effectiveness of these medications in facilitating significant and sustainable weight loss has led to their widespread adoption. At TrimRx, our comprehensive service includes doctor consultations, medication, lab work, unlimited support, and shipping with no hidden fees, all designed to make your weight loss journey safe, effective, and tailored to your individual needs. We offer compassionate care that respects every individual’s unique journey by combining advanced medical science with modern technology. Our team is dedicated to providing personalized treatment plans, which often begin with taking our free assessment quiz to determine eligibility and ensure the best fit for your health goals.

Why GLP-1 Medications Can Lead to Constipation

While the delayed gastric emptying mechanism is highly beneficial for weight loss, it is also the primary reason why many individuals experience constipation as a side effect. When food takes longer to move through the digestive system, it spends more time in the intestines. This extended transit time allows the body to reabsorb more water from the stool, making it harder, drier, and more difficult to pass. This is a common phenomenon; studies have shown that a notable percentage of individuals taking semaglutide for weight loss may experience constipation.

Beyond the direct physiological impact of slowed gastric emptying, other factors can contribute to constipation when on these medications:

• Reduced Food Intake: As GLP-1 medications help reduce appetite, individuals often consume less food overall. While beneficial for weight loss, this can sometimes lead to a decrease in dietary fiber and fluid intake, both of which are crucial for regular bowel movements.
• Changes in Dietary Habits: Some individuals might inadvertently reduce their consumption of fiber-rich foods while focusing on calorie restriction, further exacerbating the issue.
• Dehydration: Although not always a direct side effect of the medication itself, feeling fuller might lead some to drink less water throughout the day. Dehydration causes the body to pull more water from the stool, intensifying constipation.

The experience of constipation can manifest in various ways, from infrequent bowel movements to abdominal discomfort, bloating, and straining. While often mild and temporary, for some, it can be persistent and significantly impact their comfort and adherence to the treatment plan. This underscores the importance of a proactive approach to digestive health while on these powerful medications. We understand that side effects, though common, require attention and management, and our personalized programs are designed to address these concerns. To understand how a tailored approach can support your wellness, we encourage you to take our free assessment quiz to determine your eligibility for our prescription weight loss medications and receive a personalized treatment plan.

Can I Take a Laxative While on Semaglutide? Addressing the Core Question

For individuals experiencing constipation while on semaglutide or tirzepatide, the immediate and most pressing question often revolves around the safety and efficacy of using laxatives. It’s a valid concern, as introducing additional medications requires careful consideration and understanding of potential interactions. The good news is that, for most people, laxatives can be a safe and effective option when used appropriately and under medical guidance.

The Safety of Combining Laxatives with GLP-1s

Generally, there are no known direct negative interactions (contraindications) between semaglutide or tirzepatide and most types of laxatives. Clinical research has not identified specific harmful reactions that would make combining these medications inherently unsafe. However, this doesn’t mean that laxative use on GLP-1s should be taken lightly.

The main consideration when combining laxatives with GLP-1 medications is the potential for laxatives to slightly reduce the absorption rate of other medications. Since GLP-1s already slow gastric emptying, adding a laxative, especially one that speeds up intestinal transit significantly, could theoretically alter the absorption of the GLP-1 medication. However, this effect is typically minor and not a widespread concern for most individuals, especially with judicious use of appropriate laxative types.

The paramount importance lies in communicating openly with your healthcare provider. If you are experiencing constipation while on semaglutide or tirzepatide, it is essential to discuss it with your doctor or the TrimRx clinical team. They can assess your specific situation, recommend the most suitable type of laxative, advise on dosage, and monitor your progress to ensure your safety and the continued effectiveness of your weight loss medication. At TrimRx, our comprehensive service is designed to offer this level of support, including doctor consultations and unlimited communication, ensuring that we guide you through every aspect of your journey with expertise and care. Our approach remains consistent regardless of dosage changes, emphasizing our commitment to transparent and supportive service. If you’re seeking this personalized guidance, we invite you to take our free assessment quiz to explore how our programs can support your health needs.

Different Types of Laxatives and Their Mechanisms

When considering laxatives, it’s helpful to understand the various types available and how they work. This knowledge, combined with professional advice, can help you choose the most appropriate option for your needs.

Bulk-Forming Laxatives

These are often considered the gentlest and safest type of laxative for long-term use, mimicking the action of dietary fiber. They work by absorbing water in the intestines, which increases the bulk and softness of the stool. This added volume stimulates the natural contractions of the bowel, making stool easier to pass.

• Examples: Psyllium (e.g., Metamucil), Methylcellulose (e.g., Citrucel).
• Mechanism: They form a gel-like substance that adds volume to the stool, promoting bowel regularity.
• Important Note: Adequate fluid intake is absolutely critical when using bulk-forming laxatives to prevent the fiber from causing an obstruction.

Osmotic Laxatives

Osmotic laxatives work by drawing water into the intestines from the surrounding tissues. This softens the stool and increases the fluid content in the colon, which helps stimulate bowel movements. They are generally effective and well-tolerated.

• Examples: Magnesium hydroxide (e.g., Milk of Magnesia), Polyethylene Glycol 3350 (e.g., MiraLAX).
• Mechanism: They pull water into the bowel lumen, hydrating and softening the stool, making it easier to pass.
• Considerations: Like bulk-forming laxatives, staying well-hydrated is important to maximize their effectiveness and prevent dehydration.

Stool Softeners

These laxatives work by helping the stool absorb more water and fat, making it softer and easier to pass. They don’t stimulate bowel movements directly but rather make the existing stool more comfortable to evacuate.

• Example: Docusate sodium (e.g., Colace).
• Mechanism: They reduce the surface tension of the stool, allowing water to penetrate and soften it.
• Use: Often recommended for situations where straining should be avoided, such as after surgery or if experiencing hemorrhoids.

Stimulant Laxatives

Stimulant laxatives work by directly irritating the intestinal wall, causing the muscles in the intestines to contract and push stool through. They are typically faster-acting but are generally not recommended for regular or long-term use due to the risk of dependency and potential for abdominal cramping.

• Examples: Bisacodyl (e.g., Dulcolax), Sennosides (e.g., Senna).
• Mechanism: They stimulate intestinal nerves, increasing gut motility.
• Caution: These should be used sparingly and under the guidance of a healthcare professional to avoid “lazy bowel” syndrome or electrolyte imbalances.

Natural Laxatives and Dietary Approaches

Beyond over-the-counter medications, several natural approaches can help manage constipation while on semaglutide or tirzepatide. These often involve dietary modifications that are beneficial for overall health.

• Fiber-Rich Foods: Incorporating a diet rich in fruits (prunes, berries, apples), vegetables (broccoli, leafy greens), legumes, and whole grains can naturally increase fiber intake, adding bulk and softness to stool.
• Fiber Supplements: Natural fiber supplements like psyllium husk or ground flaxseeds can be excellent additions to your diet, working similarly to bulk-forming laxatives.
• Hydration: As a recurring theme, sufficient water intake is paramount for all forms of constipation relief, especially when increasing fiber.

To support your overall wellness during your weight loss journey, TrimRx also offers quick-access supplements like our GLP-1 Daily Support and Weight Loss Boost. These are available for immediate purchase and can complement a balanced diet and healthy lifestyle. Remember, selecting the right laxative or dietary strategy should always involve a discussion with your healthcare provider to ensure it aligns with your health profile and weight loss plan.

Holistic Strategies for Constipation Relief on GLP-1s

While laxatives can provide targeted relief, a truly effective approach to managing constipation while on GLP-1 medications involves a combination of lifestyle adjustments and thoughtful consideration of your treatment plan. Embracing holistic strategies ensures not only relief from discomfort but also contributes to your overall health and the sustainability of your weight loss journey. At TrimRx, we advocate for a comprehensive approach, recognizing that successful weight management extends beyond medication alone.

Essential Lifestyle Adjustments

Many simple yet powerful lifestyle changes can significantly alleviate and even prevent constipation when taking semaglutide or tirzepatide. Integrating these habits into your daily routine can make a profound difference.

Hydration: The Foundation of Digestive Health

Dehydration is a common culprit behind constipation, and it can be exacerbated by medications that slow digestion. When your body is low on fluids, it pulls water from your stool, making it harder and more difficult to pass.

• Recommendations: Aim for at least 8-10 glasses (around 64-80 ounces) of water daily. This can be more if you are physically active or in a warm climate.
• Tips for Increasing Intake: Carry a reusable water bottle, set reminders on your phone, or infuse water with fruits like cucumber and lemon for flavor. Herbal teas (e.g., peppermint, ginger) and water-rich foods (e.g., watermelon, cucumbers, oranges) also contribute to your fluid intake.

Dietary Fiber: Gradual Increase is Key

Fiber is essential for healthy bowel function. It adds bulk to stool, which helps it move through the digestive tract, and certain types of fiber also absorb water, softening the stool.

• Soluble vs. Insoluble Fiber: Soluble fiber (found in oats, apples, beans, psyllium) dissolves in water to form a gel, which softens stool. Insoluble fiber (found in whole grains, vegetables, nuts) adds bulk and speeds up transit time. A balance of both is ideal.
• Food Examples: Integrate prunes, raspberries, broccoli, lentils, and whole-grain pasta into your diet.
• Gradual Increase: Introduce fiber-rich foods slowly over a week or two. A sudden increase can lead to bloating, gas, and discomfort. Your body needs time to adjust.
• TrimRx Integration: While focusing on whole foods is paramount, our GLP-1 Daily Support can also contribute to your daily wellness efforts, providing additional support for your body’s needs as you focus on improving dietary habits.

Regular Physical Activity

Movement stimulates the muscles in your intestines, helping to promote regular bowel movements. Even moderate exercise can significantly improve gut motility.

• Beneficial Activities: A daily 20-30 minute walk can be highly effective. Other gentle movements like yoga or stretching, especially after meals, can also aid digestion. Consider incorporating a mix of aerobic exercises and strength training for overall health benefits.
• Consistency is Key: The goal is consistent, gentle movement rather than intense, sporadic workouts.

Mindful Eating Practices

How you eat is almost as important as what you eat. Mindful eating can support healthy digestion and prevent discomfort.

• Slow Down: Eating too quickly can lead to swallowing air, causing gas and bloating. Take your time, chew your food thoroughly, and savor each bite.
• Portion Control: Overeating can overburden your digestive system. Listen to your body’s hunger and fullness cues to avoid discomfort.

Optimizing Your GLP-1 Treatment with TrimRx

Beyond lifestyle changes, the design and supervision of your GLP-1 treatment play a crucial role in managing side effects like constipation. At TrimRx, we emphasize a personalized and supportive approach.

Personalized Care and Dosages

The intensity of side effects, including constipation, can sometimes be linked to the dosage of your medication. Starting with a lower dose and gradually increasing it (titration) allows your body to adjust more smoothly, potentially mitigating digestive issues.

• TrimRx Approach: We understand that every individual’s body responds differently. Our programs are built on personalized treatment plans, developed after a thorough assessment. Our team works closely with you to find the optimal dosage that balances effectiveness with minimal side effects. We believe that sustainable weight loss should be achieved through science, empathy, and a transparent approach, and this commitment to individualized care is central to our method. If you haven’t yet, we invite you to take our free assessment quiz to discover your personalized treatment path.

The Role of Comprehensive Support

Our brand is empathetic, innovative, trustworthy, supportive, results-oriented, and personalized. We offer compassionate care that respects every individual’s unique journey by combining advanced medical science with modern technology. This means providing support that goes beyond just medication.

• Included Services: Our comprehensive service includes doctor consultations, necessary lab work, and unlimited support to address any concerns you may have, including side effects like constipation. We also handle shipping of your medication with no hidden fees, working exclusively with FDA-registered and inspected pharmacies for products like Compounded Semaglutide, Oral Semaglutide, Ozempic®, Compounded Tirzepatide, Oral Tirzepatide, Mounjaro®, Zepbound®, and Wegovy®. It’s important to clarify that TrimRx partners with these pharmacies for the shipping of weight loss medications and does not provide actual medical supervision; medical guidance is provided by the licensed healthcare professionals within our network. Our commitment to transparent service highlights that our approach remains consistent regardless of dosage changes.
• Empowering You: We believe that with the right support and strategies, you can successfully manage any challenges that arise, ensuring that your weight loss journey remains positive and productive. Our clinical team is always available to discuss your concerns, offer advice, and adjust your plan as needed. For immediate support for your overall wellness during this journey, consider our Weight Loss Boost supplement.

By combining proactive lifestyle adjustments with the expert guidance and personalized care offered by TrimRx, you can navigate constipation effectively, maintaining your comfort and focus on achieving your health goals.

When to Seek Professional Guidance

While many instances of constipation on semaglutide or tirzepatide can be managed with lifestyle adjustments and appropriate over-the-counter laxatives, it is crucial to recognize when professional medical attention is warranted. Sometimes, what seems like simple constipation could be a sign of a more serious underlying issue, especially with medications that affect the digestive system. At TrimRx, your safety and well-being are our highest priorities, and we strongly encourage seeking expert advice when concerns arise.

Recognizing Serious Symptoms

It is important to differentiate between common, manageable constipation and more severe digestive complications. While most gastrointestinal side effects associated with GLP-1 medications are mild and transient, a few serious conditions, though rare, have been observed. You should contact your healthcare provider immediately if you experience any of the following symptoms:

• Persistent Constipation: If constipation lasts for more than two weeks despite lifestyle changes and OTC laxatives, it’s time to seek medical advice.
• Severe Abdominal Pain or Cramping: Intense, unrelenting pain in the abdomen should never be ignored.
• Significant Pain During Bowel Movements: While straining can be uncomfortable, sharp or severe pain during defecation is a red flag.
• Blood in Your Stool: Any presence of blood (bright red or dark/tarry) requires immediate medical evaluation.
• Persistent Nausea and Vomiting: If nausea and vomiting are severe, don’t subside, or if vomit contains blood or resembles “coffee grounds,” seek urgent care.
• Abdominal Distension or Bloating that Won’t Stop: Excessive and persistent bloating that is not relieved by passing gas or stool.

These symptoms could indicate rare but serious conditions such as:

• Gastroparesis (Stomach Paralysis): A disorder where the stomach muscles work poorly or not at all, preventing food from emptying properly. While GLP-1s intentionally slow gastric emptying, extreme slowing can lead to gastroparesis, causing severe pain, malnutrition, and other serious issues.
• Intestinal Blockage: This occurs when food or feces cannot move through the intestines, potentially leading to a backup. It can be caused by various factors, including severely slowed motility.
• Ileus (Non-Mechanical Bowel Obstruction): Similar to gastroparesis, this is a condition where the intestinal muscles stop moving properly, leading to an obstruction without a physical blockage.
• Gallbladder Problems: Some studies have indicated an increased risk of gallbladder issues, such as gallstones, with rapid weight loss and GLP-1 use. Symptoms can include severe pain in the upper right abdomen, nausea, vomiting, or jaundice.
• Potential Vision Loss: Although more research is needed, some reports and studies have explored a potential link between semaglutide use and a serious eye condition known as nonarteritic anterior ischemic optic neuropathy (NAION), which can cause sudden vision loss.

While these serious side effects are not common, awareness and prompt medical attention are crucial if they arise. Your healthcare provider can conduct a thorough assessment, which may include further tests, to rule out or diagnose any serious conditions and adjust your treatment plan accordingly.

How TrimRx Supports Your Health Journey

At TrimRx, we are committed to providing you with a safe and effective weight loss journey, which includes vigilant monitoring and access to expert medical guidance. We believe that sustainable weight loss should be achieved through science, empathy, and a transparent approach, ensuring your health and safety are always paramount.

• Expert Consultations: Our personalized programs begin with thorough doctor consultations to assess your health history and current condition. This ensures that any weight loss medication prescribed, such as Compounded Semaglutide, Oral Semaglutide, Ozempic®, Compounded Tirzepatide, Oral Tirzepatide, Mounjaro®, Zepbound®, or Wegovy®, is appropriate for you. We partner with FDA-registered and inspected pharmacies for the shipping of these medications, focusing on safety and quality.
• Ongoing Support: We offer unlimited support throughout your journey, allowing you to easily communicate any side effects or concerns with our clinical team. This continuous oversight helps us to swiftly address issues like persistent constipation or other symptoms, adjusting your plan as needed.
• Empowering Informed Decisions: We provide clear, comprehensive information about your treatment, potential side effects, and when to seek further medical attention. This empowers you to make informed decisions about your health in partnership with our dedicated team.

If you are experiencing any concerning symptoms or have questions about managing constipation on your GLP-1 medication, do not hesitate to reach out. Your proactive engagement, combined with our compassionate and results-oriented care, forms the foundation for a successful and healthy weight loss journey. To start your journey with expert support and a personalized plan, take our free assessment quiz today.

Conclusion

The journey toward a healthier weight with the support of GLP-1 medications like semaglutide and tirzepatide offers incredible promise, transforming lives through effective appetite regulation and metabolic improvements. However, as we’ve explored, this path can sometimes bring unexpected challenges, with constipation being a common side effect that can impact comfort and adherence. The good news is that managing constipation while on these medications is entirely achievable through a combination of informed choices and proactive strategies.

We’ve established that the answer to “can I take a laxative while on semaglutide?” is generally yes, but it hinges on careful consideration and, most importantly, open communication with your healthcare provider. Understanding the different types of laxatives—from gentle bulk-forming and osmotic options to stool softeners and, with caution, stimulants—empowers you to make educated choices under professional guidance. While laxatives offer relief, they are best integrated into a broader strategy that prioritizes essential lifestyle adjustments.

The cornerstone of digestive health on GLP-1 medications lies in consistent hydration, a gradual increase in dietary fiber, regular physical activity, and mindful eating practices. These habits not only alleviate constipation but also contribute significantly to your overall well-being and the sustained success of your weight loss efforts. Furthermore, recognizing when symptoms might signal a more serious underlying issue and seeking prompt medical attention is paramount for your safety and peace of mind.

At TrimRx, we are dedicated to being your trusted partner on this transformative journey. Our brand is built on empathy, innovation, and a commitment to personalized, medically supervised care. We understand that each individual’s journey is unique, which is why our platform offers comprehensive support, including doctor consultations, lab work, unlimited assistance, and the convenient shipping of clinically proven medications like Compounded Semaglutide, Oral Semaglutide, Ozempic®, Compounded Tirzepatide, Oral Tirzepatide, Mounjaro®, Zepbound®, and Wegovy® through our network of FDA-registered and inspected pharmacies. Our transparent approach ensures consistent service and support, irrespective of dosage adjustments.

We believe that sustainable weight loss should be achieved through science, empathy, and a transparent approach, allowing you to embrace a healthier lifestyle with confidence and comfort. Don’t let digestive discomfort deter you from your goals. Equip yourself with knowledge, leverage supportive resources, and always prioritize open communication with your healthcare team.

To explore a personalized weight loss plan tailored to your unique needs and to receive expert guidance on managing all aspects of your journey, we encourage you to take our free assessment quiz today. Additionally, for immediate support for your overall wellness, consider our quick-access supplements: GLP-1 Daily Support and Weight Loss Boost. Together, we can ensure your path to a healthier you is as smooth and successful as possible.

Frequently Asked Questions

How long does constipation typically last when taking semaglutide or similar GLP-1 medications?

The duration of constipation can vary significantly among individuals. For some, it may be a temporary side effect that subsides within the first few weeks as their body adjusts to the medication. Clinical trials have sometimes noted improvement around the 7-week mark. However, for others, constipation can persist longer, requiring ongoing management through lifestyle changes or laxatives. It’s crucial to address it promptly to maintain comfort and prevent it from becoming chronic.

Are certain types of laxatives better than others when on semaglutide?

Yes, generally, bulk-forming laxatives (like psyllium and methylcellulose) and osmotic laxatives (like magnesium hydroxide and polyethylene glycol 3350) are often recommended as a first line due to their gentle action and lower risk of dependency. These work by adding bulk or drawing water into the stool, making it softer and easier to pass. Stimulant laxatives should be used sparingly and only under medical guidance due to the potential for dependency and cramping. Always discuss your options with a healthcare professional to determine the best choice for your individual needs.

What are the signs of a serious issue related to constipation while on GLP-1 medications?

While mild constipation is common, certain symptoms warrant immediate medical attention. These include severe or persistent abdominal pain, cramping, or bloating, blood in your stool (bright red or dark/tarry), persistent nausea and vomiting (especially if vomit contains blood or looks like coffee grounds), inability to pass gas, or constipation lasting longer than two weeks despite home remedies. These could indicate more serious conditions like gastroparesis, intestinal blockage, or other complications that require urgent medical evaluation.

Can I prevent constipation on semaglutide, or is it an unavoidable side effect?

Constipation is a common side effect, but it is often preventable or significantly manageable with proactive measures. Key strategies include maintaining excellent hydration by drinking plenty of water throughout the day, gradually increasing your dietary fiber intake through fruits, vegetables, and whole grains, and engaging in regular physical activity. Starting your GLP-1 medication at a lower dose and slowly titrating up, as guided by your healthcare provider, can also help your body adjust and potentially reduce the severity of digestive side effects. Our personalized TrimRx programs are designed to help you implement these strategies effectively.