Navigating Your Diet: Do You Eat on Ozempic® and What Changes to Expect?

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45 min
Published on
December 12, 2025
Updated on
December 12, 2025
Navigating Your Diet: Do You Eat on Ozempic® and What Changes to Expect?

Introduction

Imagine waking up one day and feeling a profound shift in your relationship with food – less intense cravings, a quicker sense of fullness, and a diminished focus on eating. This experience is becoming a reality for many individuals embarking on a weight loss journey with GLP-1 medications like Ozempic®. The rise of these innovative treatments has sparked a crucial question for those considering or currently using them: do you eat on Ozempic®, and what fundamental dietary adjustments are truly necessary for success?

The landscape of weight management is continually evolving, with groundbreaking advancements offering new hope and effective tools. Medications such as Ozempic® (semaglutide), Zepbound® (tirzepatide), Wegovy® (semaglutide), and Mounjaro® (tirzepatide) – alongside compounded versions of semaglutide and tirzepatide – have emerged as powerful allies in managing weight and associated health conditions like type 2 diabetes. These prescription medications work by mimicking natural hormones to influence appetite, satiety, and metabolism, fundamentally altering how your body processes and responds to food. However, their effectiveness isn’t a standalone miracle; it’s profoundly amplified by a thoughtful, intentional approach to diet.

This post aims to demystify the dietary considerations when using GLP-1 medications. We will delve into the science behind how these medications interact with your body, clarify which foods can enhance their benefits, and identify those that might exacerbate side effects or hinder progress. Our purpose is to provide you with a comprehensive, evidence-based understanding that empowers you to make informed choices, optimize your results, and cultivate sustainable habits for long-term well-being. By the end of this article, you will not only understand the necessity of dietary changes but also gain practical strategies for integrating them seamlessly into your daily life. Together, we’ll explore how to harmonize the pharmacological support of these medications with nourishing eating patterns, ensuring a truly holistic and effective path to a healthier you. This journey requires a partnership between medication and lifestyle, and we’re here to guide you through every step.

The Science Behind Feeling Full: How GLP-1 Medications Work

To truly understand the dietary shifts required when asking, “do you eat on Ozempic®?”, it’s essential to first grasp the remarkable science underpinning these medications. At TrimRx, our journey began with a shared vision to help individuals embrace healthier lifestyles by merging cutting-edge telehealth innovations with effective weight loss solutions. Our approach is rooted in understanding the intricate mechanisms that govern our bodies, ensuring that our solutions are both innovative and scientifically sound.

Understanding Semaglutide and Tirzepatide

Ozempic® and Wegovy® both contain the active ingredient semaglutide, while Mounjaro® and Zepbound® contain tirzepatide. These medications belong to a class known as GLP-1 receptor agonists (glucagon-like peptide-1). Tirzepatide, in particular, is unique as it also acts on glucose-dependent insulinotropic polypeptide (GIP) receptors, making it a dual GIP and GLP-1 receptor agonist. This dual action can lead to even more pronounced effects on blood sugar control and weight loss.

These medications are not just for weight loss; for individuals with type 2 diabetes, Ozempic® and Mounjaro® are FDA-approved to improve blood sugar control. Ozempic® is also approved to reduce the risk of major cardiovascular events in adults with type 2 diabetes and known heart disease. Wegovy® and Zepbound® are specifically FDA-approved for chronic weight management in adults with obesity or overweight with at least one weight-related condition.

When we talk about personalized weight loss programs, it’s important to remember that our medications, including Ozempic®, Wegovy®, Mounjaro®, Zepbound®, and our compounded semaglutide and tirzepatide options, are provided through FDA-registered and inspected pharmacies. It’s crucial to note that while branded medications like Ozempic® and Zepbound® are FDA-approved, compounded medications are not. We prioritize your safety by working exclusively with pharmacies that meet stringent quality and safety standards.

The Role of GLP-1 in Appetite and Digestion

GLP-1 is a natural hormone produced in your gut that plays a critical role in regulating appetite and glucose metabolism. When you take a GLP-1 receptor agonist like semaglutide or tirzepatide, it mimics the action of this natural hormone, leading to several key physiological effects:

  1. Enhanced Satiety: These medications signal to your brain that you are full, significantly reducing “food noise” – the constant thoughts and cravings related to eating. This effect helps you feel satisfied with smaller portions and less frequently throughout the day.
  2. Slowed Gastric Emptying: GLP-1s slow down how quickly food moves from your stomach to your intestines. This means food stays in your stomach for a longer period, contributing to prolonged feelings of fullness.
  3. Blood Sugar Regulation: For those with type 2 diabetes, these medications stimulate insulin release in a glucose-dependent manner (only when blood sugar is high) and suppress glucagon secretion, which helps lower blood sugar levels.

The combined effect of these mechanisms is a powerful reduction in appetite and caloric intake, paving the way for weight loss. However, this feeling of fullness doesn’t automatically dictate what you should eat. The profound reduction in appetite necessitates a strategic approach to nutrition, ensuring that the fewer calories you consume are packed with essential nutrients. This is where our personalized, medically supervised care comes into play, making sustainable weight loss attainable and tailored to the individual. If you’re wondering if these solutions are right for you, we encourage you to take our free assessment quiz to determine your eligibility and receive a personalized treatment plan.

Do You Eat on Ozempic®? The Essential Dietary Shift

The question of “do you eat on Ozempic®” is not just about if but how you eat. While the medication significantly reduces appetite, it doesn’t eliminate the need for conscious, healthy eating. In fact, optimizing your diet becomes even more critical to maximize benefits and mitigate potential side effects.

Why Dietary Changes are Non-Negotiable

GLP-1 medications are powerful tools, but they are most effective when integrated into a comprehensive weight management strategy that includes dietary modifications and regular physical activity. Clinical trials have consistently shown that participants achieve the most significant weight loss when these medications are combined with a reduced-calorie diet and increased exercise. Relying solely on the medication without adjusting eating habits can diminish its overall impact and may lead to a less sustainable outcome.

Moreover, the physiological changes induced by these medications, particularly slowed gastric emptying, mean that certain foods can exacerbate common side effects like nausea, vomiting, constipation, or diarrhea. Therefore, understanding which foods to favor and which to limit is not merely about weight loss, but also about improving comfort and adherence to your treatment plan. Our brand is empathetic and supportive, and we offer compassionate care that respects every individual’s unique journey by combining advanced medical science with modern technology. We believe in transparency and empowering you with the knowledge to navigate your journey safely and effectively.

Embracing a Calorie-Conscious, Nutrient-Dense Approach

With a reduced appetite, every calorie you consume becomes more important. The goal is to create a sustainable calorie deficit while ensuring your body receives all the necessary macronutrients (protein, carbohydrates, fats) and micronutrients (vitamins, minerals). This means shifting away from calorie-dense, nutrient-poor foods towards options that offer high nutritional value per calorie.

Many clinical guidelines recommend aiming for a daily calorie deficit, often in the range of 500-600 calories less than your body burns, to promote sustainable weight loss. However, this shouldn’t lead to overly restrictive or unbalanced diets, which can be counterproductive and foster unhealthy relationships with food. Instead, the focus should be on building lasting habits around wholesome, nourishing foods. This personalized approach to nutrition is a cornerstone of our philosophy at TrimRx, ensuring you receive tailored guidance for building habits that endure. We offer a comprehensive service that includes doctor consultations, medication, lab work, unlimited support, and shipping with no hidden fees, all designed to make your journey as smooth as possible.

Fueling Your Body Right: What to Eat on Ozempic® and Other GLP-1s

When asking, “do you eat on Ozempic®?” the answer involves a strategic selection of foods that support your weight loss goals and minimize side effects. Focusing on nutrient-dense foods will not only keep you feeling satisfied but also provide essential energy and well-being.

Prioritizing Lean Proteins for Satiety and Muscle Preservation

Protein is arguably the most critical macronutrient when taking GLP-1 medications. It’s essential for several reasons:

  • Satiety: Protein is highly satiating, meaning it helps you feel full for longer, which is crucial when you’re eating smaller portions.
  • Muscle Preservation: As you lose weight, there’s a risk of losing muscle mass along with fat. Adequate protein intake helps preserve lean muscle, which is vital for maintaining a healthy metabolism and overall strength.
  • Nutrient Density: Lean protein sources often come packed with other essential vitamins and minerals.

Aim for a consistent intake of lean protein throughout your day, incorporating it into every meal. Good sources include:

  • Animal-based: Skinless chicken or turkey breast, lean cuts of beef, fish (salmon, cod, tuna, tilapia), seafood (shrimp, scallops), eggs, Greek yogurt, cottage cheese.
  • Plant-based: Tofu, tempeh, edamame, lentils, beans, quinoa, nuts, seeds, and plant-based protein powders.

While specific protein needs vary by individual, many recommendations suggest 1.0 to 1.2 grams of protein per kilogram of body weight. For someone weighing 185 pounds, this could mean aiming for roughly 84 to 101 grams of protein daily. Prioritize consuming protein first during meals, especially if you find yourself getting full quickly.

The Power of Fruits and Non-Starchy Vegetables

Fruits and non-starchy vegetables are powerhouses of nutrition. They are generally low in calories, high in fiber, and rich in essential vitamins, minerals, and antioxidants.

  • Fiber-Rich: The high fiber content promotes digestive health and contributes to feelings of fullness, further aiding in appetite control.
  • Hydrating: Many fruits and vegetables have a high water content, helping you stay hydrated, which is especially important if you experience gastrointestinal side effects.
  • Nutrient Support: They provide critical nutrients that may otherwise be missed with a reduced caloric intake, supporting energy levels and overall immune function.

Strive to fill at least half of your plate with a colorful variety of non-starchy vegetables. Examples include leafy greens (spinach, kale), bell peppers, mushrooms, tomatoes, onions, carrots, cucumbers, zucchini, asparagus, and artichoke hearts. For fruits, enjoy them in moderation, aiming for 1.5-2 cups daily, focusing on options lower in sugar like berries, kiwi, grapefruit, and peaches. Remember that diversity in color ensures a broad spectrum of beneficial phytonutrients.

Incorporating Healthy Fats and Smart Carbohydrates

Healthy fats are crucial for hormone production, nutrient absorption (especially fat-soluble vitamins), and satiety. Focus on unsaturated fats from sources like:

  • Avocados
  • Nuts and seeds (almonds, walnuts, chia seeds, flax seeds)
  • Olive oil
  • Fatty fish (salmon, mackerel)

While some individuals might experience increased side effects from high-fat foods due to slowed digestion, incorporating healthy fats in moderation, in line with your individual tolerance, is generally beneficial.

When it comes to carbohydrates, prioritize whole grains over refined ones. Whole grains contain fiber, which slows digestion, prevents rapid blood sugar spikes, and provides sustained energy.

  • Whole grains: Brown rice, whole wheat bread and pasta, oats, quinoa, farro, bulgur, barley.
  • Starchy vegetables: Potatoes, sweet potatoes, butternut squash, pumpkin (consume these in moderation, treating them as part of your carbohydrate portion, typically making up about a quarter of your plate).

By making these thoughtful choices, you ensure that your body is adequately fueled and supported throughout your weight loss journey. This is the essence of personalized care – understanding your body’s needs and adjusting your diet accordingly. If you’re looking for additional support, our GLP-1 Daily Support supplement can complement your journey.

Smart Hydration Strategies

Staying adequately hydrated is paramount, especially when taking GLP-1 medications. Side effects like nausea, vomiting, or diarrhea can lead to fluid loss and dehydration, potentially causing kidney problems.

  • Water is Key: Make water your primary beverage. Sip throughout the day, even if you don’t feel thirsty.
  • Electrolyte-Rich Fluids: If experiencing significant fluid loss, consider adding electrolyte-rich drinks in moderation, avoiding those high in sugar.
  • Avoid Dehydrating Beverages: Limit or avoid sugary sodas, excessive caffeine (especially with added sugars/creams), and alcohol, as these can exacerbate dehydration and sometimes worsen gastrointestinal discomfort.
  • High Water Content Foods: Incorporate soups, broths, and water-rich fruits and vegetables into your diet.

Navigating Potential Discomfort: Foods to Approach with Caution

As you discover how you eat on Ozempic®, you’ll find that certain foods can significantly impact your comfort and progress due to the medication’s effects. Being mindful of these can help you manage side effects and optimize your experience.

High-Fat and Greasy Foods: A Recipe for Trouble?

Due to the slowed gastric emptying caused by GLP-1 medications, high-fat and greasy foods can linger in the stomach for an extended period. This can intensify common side effects such as nausea, vomiting, bloating, and indigestion. Think about typical fast-food items like:

  • Deep-fried foods (fried chicken, French fries)
  • Fatty meats (burgers, processed sausages)
  • Rich dairy products (creamy sauces, excessive cheese, butter)
  • Ultra-processed snacks (many crisps, pastries, cookies)

These foods are not only calorie-dense and nutrient-poor, working against your weight loss goals, but they can also make you feel physically uncomfortable. Eating meals high in fat has been shown to cause nausea in people with delayed stomach emptying. It’s often beneficial to reduce or avoid these items to support both your weight management and your digestive comfort.

The Impact of High Glycemic Index Foods

Foods with a high glycemic index (GI) are rapidly digested and absorbed, causing quick spikes in blood sugar. While GLP-1 medications help regulate blood sugar, consuming an excess of high-GI foods can still challenge your system and potentially undermine weight loss efforts. These typically include:

  • Sugary beverages (sodas, sweetened juices)
  • Refined grains (white bread, white pasta, sugary cereals)
  • Sweets and candies
  • Pastries and baked goods

When blood sugar rises too quickly, your body may release more insulin than needed, which can signal the body to store excess sugar as fat. Opting for complex carbohydrates (whole grains, legumes) and natural sugars from fruits, which come with fiber, helps to ensure a more gradual rise in blood sugar and sustained energy.

Rethinking Portion Sizes: Less Can Be More

One of the most noticeable effects of GLP-1 medications is a reduced appetite and increased satiety. This means you will likely feel full much faster than before. Attempting to eat the same large portions you were accustomed to before starting medication can lead to discomfort, nausea, and a feeling of being “overstuffed.”

  • Smaller, More Frequent Meals: Many individuals find that eating smaller, more frequent meals throughout the day is more manageable and reduces pressure on the digestive system.
  • Listen to Your Body: Pay close attention to your body’s hunger and fullness cues. Stop eating when you feel comfortably satisfied, not uncomfortably full. Since the gut takes longer to empty, smaller meals can alleviate bloating and other gastric symptoms.
  • Mindful Eating: Eating slowly, chewing thoroughly, and putting down your utensils between bites can help your brain register fullness, preventing accidental overeating.

Considerations for Raw Vegetables, Spicy Foods, Alcohol, and Caffeinated Beverages

Beyond fats and sugars, other dietary components warrant consideration:

  • Raw and Cruciferous Vegetables: While highly nutritious, some raw and cruciferous vegetables (like broccoli, cabbage, and cauliflower) can cause gas and bloating, which might be intensified by slowed digestion. Cooking these vegetables can make them easier to digest.
  • Highly Spiced Foods: Spicy foods can irritate the digestive tract and potentially exacerbate nausea or heartburn, which are common side effects of GLP-1 medications. Opt for milder seasonings, especially if you’re experiencing stomach upset.
  • Alcohol: Alcohol can worsen nausea and vomiting. It can also potentially lower blood sugar, which might be a concern for some individuals. If you choose to drink, do so in very strict moderation, adhering to general health guidelines of one drink per day for women and two for men.
  • Caffeinated Beverages: While plain coffee might be tolerated, excessively sweetened or creamy coffee drinks can add unnecessary calories and fats, making them less ideal for your diet plan.

By thoughtfully adjusting your food choices and portion sizes, you can significantly enhance your comfort and the overall effectiveness of your GLP-1 medication. This careful approach to diet, combined with the comprehensive service we offer at TrimRx—including doctor consultations, medication, lab work, unlimited support, and shipping with no hidden fees—forms a powerful strategy for sustainable weight loss.

Beyond the Plate: Cultivating Sustainable Eating Habits

The journey with GLP-1 medications like Ozempic® is about more than just what you eat; it’s about transforming your relationship with food and embedding lasting, healthy habits. At TrimRx, we believe that sustainable weight loss should be achieved through science, empathy, and a transparent approach, extending far beyond the initial phase of medication.

Mindful Eating Practices

Mindful eating is a powerful tool, especially when your appetite is reduced by medication. It encourages you to pay attention to the experience of eating, listen to your body’s signals, and savor your food.

  • Eat Slowly: Give your brain time to register fullness. It often takes about 20 minutes for satiety signals to fully kick in.
  • Chew Thoroughly: This aids digestion and allows you to enjoy the flavors and textures of your food more fully.
  • Eliminate Distractions: Turn off the TV, put away your phone, and focus solely on your meal.
  • Recognize Hunger and Fullness Cues: Learn to distinguish between true physical hunger and emotional or habitual eating. Stop when you are comfortably satisfied, not painfully full.
  • Keep a Food Diary: Tracking what you eat, when you eat, and how you feel can help identify patterns and triggers, allowing you to make more informed choices. This also helps pinpoint foods that might exacerbate side effects.

These practices, when consistently applied, can help you develop an intuitive understanding of your body’s needs, fostering a healthier, more balanced eating pattern that can be maintained long after you reach your weight goals.

The Importance of Professional Guidance

While this article provides extensive guidance, navigating dietary changes, especially alongside medication, can be complex. This is why professional support is invaluable.

  • Registered Dietitians (RDs): An RD can provide personalized meal plans, nutritional education, and strategies tailored to your specific health needs, lifestyle, and food preferences. They can help you ensure adequate nutrient intake, manage side effects through diet, and build sustainable habits. Many insurance plans cover dietitian appointments for individuals with an obesity diagnosis.
  • Healthcare Providers: Regular check-ins with your prescribing doctor are crucial. They can monitor your progress, manage medication dosages, and address any persistent side effects or concerns. If you’re experiencing severe side effects or believe you might not be getting enough calories, discuss this with your healthcare provider promptly.

Studies consistently show that individuals tend to achieve more significant and sustainable weight loss when they have access to both weight loss medication and comprehensive support for healthy lifestyle changes. This integrated approach is at the core of TrimRx’s philosophy. Our brand is trustworthy, supportive, and results-oriented. We combine advanced medical science with modern technology to deliver compassionate care.

How TrimRx Supports Your Journey

At TrimRx, we understand that weight loss is a personal and often challenging journey. Our platform is a user-friendly and supportive space where individuals receive personalized, medically supervised care. We believe in empowering you with the tools and knowledge for lasting success.

Our comprehensive service includes doctor consultations to assess your eligibility and create a tailored plan, necessary lab work, the prescription medication itself (sourced from FDA-registered and inspected pharmacies), and unlimited support throughout your journey. We pride ourselves on transparent service, ensuring our approach remains consistent regardless of dosage changes, with no hidden fees. We are dedicated to providing you with everything you need to feel confident and supported as you embrace a healthier lifestyle.

Maximizing Your Weight Loss Journey with Personalized Support

Your path to weight loss is unique, and at TrimRx, we celebrate that individuality by offering solutions that are as personalized as you are. Understanding “do you eat on Ozempic®” is a significant step, but integrating that knowledge requires a structured and supportive framework.

Discovering Your Path with TrimRx’s Personalized Assessment

For those considering prescription weight loss medications like Compounded Semaglutide, Oral Semaglutide, Ozempic®, Compounded Tirzepatide, Oral Tirzepatide, Mounjaro®, Zepbound®, or Wegovy®, the first step is to ensure it’s the right fit for your health profile. Our empathetic and innovative approach begins with a comprehensive, free assessment.

By taking our free assessment quiz to determine your eligibility and receive a personalized treatment plan, you embark on a journey towards a medically supervised plan tailored specifically to your needs. This assessment helps our healthcare providers understand your health history, current conditions, and weight loss goals, allowing us to recommend the most appropriate and effective treatment options. It’s designed to be a supportive entry point into a program that prioritizes your safety and long-term success.

Enhancing Your Journey with Quick-Access Support

Beyond prescription medications, we understand that ongoing support for overall wellness is crucial. To complement your personalized weight loss program or to simply support your healthy lifestyle efforts, we offer quick-access supplements that do not require a quiz for purchase. These supplements are designed to provide additional nutritional support and enhance your well-being.

  • GLP-1 Daily Support: This supplement is formulated to provide daily nutritional support, working in harmony with your body’s natural processes to help you feel your best. It’s an excellent option for those looking to maintain consistent energy and digestive comfort.
  • Weight Loss Boost: Designed to give your weight loss efforts an extra edge, this supplement offers targeted ingredients to support metabolism and aid in your journey.

These quick-access supplements reflect our commitment to offering a holistic suite of solutions, reinforcing that we are here to support every aspect of your health and weight loss journey. Whether through personalized medication plans or immediate wellness support, TrimRx is your trusted partner in achieving sustainable results. We are results-oriented and dedicated to providing personalized care that truly makes a difference in your life.

Conclusion

The question, “do you eat on Ozempic®,” opens the door to a deeper understanding of how modern medical advancements, coupled with informed dietary choices, can revolutionize weight management. We’ve explored the intricate science behind GLP-1 medications like Ozempic®, Wegovy®, Mounjaro®, and Zepbound®, understanding how they influence appetite, digestion, and blood sugar. This knowledge underscores that while these medications are powerful tools, their optimal effectiveness is unlocked through a conscious and strategic approach to nutrition.

We’ve highlighted the crucial role of a calorie-conscious, nutrient-dense diet, emphasizing the importance of lean proteins, diverse fruits and non-starchy vegetables, healthy fats, and smart carbohydrates. Just as importantly, we’ve discussed foods to approach with caution – high-fat, high-GI, and overly large portions – to mitigate potential side effects and ensure a more comfortable journey. Beyond specific food groups, the power of mindful eating and the invaluable support of healthcare professionals and dietitians were brought to light as foundational elements for cultivating sustainable habits.

At TrimRx, we are dedicated to safe, effective weight loss and individualized care. Our platform merges cutting-edge telehealth with personalized, medically supervised programs designed to make sustainable weight loss attainable. We stand by our commitment to science, empathy, and transparency, ensuring that you receive compassionate care and transparent service at every step. From a personalized assessment to determine your eligibility for prescription medications, to immediate support supplements like GLP-1 Daily Support and Weight Loss Boost, we provide a comprehensive approach to empower your journey.

Remember, this is not just about losing weight; it’s about building a healthier, more vibrant life. What small, sustainable dietary change can you commit to today that will make a significant impact on your well-being? If you’re ready to explore how a personalized, medically supervised plan can transform your health, we invite you to take our free assessment quiz to determine your eligibility and receive a personalized treatment plan. Your journey towards sustainable health starts now, and we’re here to support you every step of the way.

Frequently Asked Questions (FAQs)

What types of foods are best to eat while taking Ozempic® or similar GLP-1 medications?

When taking Ozempic® or other GLP-1 medications, it’s best to focus on a nutrient-dense, reduced-calorie diet rich in lean proteins (chicken, fish, tofu, beans), non-starchy vegetables (leafy greens, bell peppers), and moderate amounts of healthy fats (avocado, nuts) and whole grains (quinoa, oats). These foods help promote satiety, preserve muscle mass, and provide essential nutrients while supporting your weight loss goals.

Are there any foods I should avoid or limit while on Ozempic® to prevent side effects?

Yes, certain foods can exacerbate common side effects like nausea, vomiting, bloating, or diarrhea due to the medication’s effect of slowing digestion. It’s generally advisable to limit or avoid high-fat and greasy foods (fried foods, fatty meats), high glycemic index foods (sugary drinks, refined carbs), highly spiced foods, and very large portions. Raw cruciferous vegetables, alcohol, and excessively sweetened caffeinated beverages should also be consumed with caution or limited based on individual tolerance.

How does Ozempic® affect my appetite, and how should I adjust my meal timing and portion sizes?

Ozempic® significantly reduces appetite and increases feelings of fullness, often leading to eating less frequently and feeling satisfied with smaller portions. It’s important to listen to your body’s new hunger and fullness cues. Many individuals find success with smaller, more frequent meals throughout the day. Eating slowly and mindfully can help prevent overeating and reduce gastrointestinal discomfort, as it gives your brain time to register satiety.

Can TrimRx help me with a personalized diet plan while on weight loss medication?

Yes, at TrimRx, we offer comprehensive, personalized support designed to complement your weight loss medication. Our service includes doctor consultations where your dietary needs and lifestyle are discussed. While we don’t provide a specific “Ozempic® diet,” our medically supervised approach ensures you receive guidance on making sustainable dietary changes. We also offer unlimited support to help you navigate your journey. To see if you qualify for our personalized prescription programs and receive a tailored treatment plan, we encourage you to take our free assessment quiz to determine your eligibility and receive a personalized treatment plan.

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