TrimRx's Blog

9 min read

Wegovy and Surgery: When to Stop Before an Operation

Introduction The current American Society of Anesthesiologists guidance, updated in 2023, recommends holding weekly GLP-1s like Wegovy® the week of elective surgery. The reason…

9 min read

Wegovy and Hair Loss: Cause and Prevention

Wegovy shedding is real but often overstated. In the STEP 1 trial (Wilding et al.

8 min read

Wegovy and Depression: Real Risk Profile

Introduction Wegovy®’s depression question has been one of the most-watched safety signals in obesity medicine since 2023, when Iceland’s regulator flagged a small cluster…

9 min read

Weekly vs Daily GLP-1: Dosing Frequency Compared

The GLP-1 class split into two dosing camps a decade ago, and the camps still matter today.

8 min read

Walking for Weight Loss on GLP-1: Why 10K Steps Works

Walking is the most underrated tool on a GLP-1 protocol.

9 min read

Vasoactive Intestinal Peptide (VIP): Gut-Brain Healing

Introduction Vasoactive intestinal peptide, usually shortened to VIP, is a 28-amino-acid neuropeptide first isolated from porcine duodenum in 1970 by Sami Said and Viktor…

11 min read

The Vagus Nerve and Weight Loss: How GLP-1 Talks to Your Gut

The vagus nerve is the longest cranial nerve in the body.

9 min read

What to Do When UnitedHealthcare Denies Zepbound: Step-by-Step Appeal

UnitedHealthcare processes pharmacy benefits through OptumRx, so Zepbound denials come back as OptumRx adverse determinations.

10 min read

What to Do When UnitedHealthcare Denies Wegovy: Appeal Strategy

UnitedHealthcare processes pharmacy benefits through OptumRx, which is the same company under the UnitedHealth Group umbrella.

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