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Sublingual GLP-1 drops claim to deliver semaglutide or tirzepatide under the tongue, skipping the needle. The pitch is attractive.

Wegovy is Novo Nordisk’s FDA-approved semaglutide for chronic weight management, approved June 2021 at the 2.4 mg weekly dose.

Ozempic is Novo Nordisk’s brand-name semaglutide injection approved by the FDA in December 2017 for type 2 diabetes.

Switching between Ozempic, Wegovy, and compounded semaglutide is straightforward because the active ingredient is identical.

Compounded semaglutide is a sterile injectable peptide that requires refrigeration between 36°F and 46°F (2°C-8°C).

Compounded semaglutide vials should be refrigerated between 36-46°F (2-8°C) until first use.

Most semaglutide side effects are gastrointestinal, mild to moderate, and concentrated in the first 8-12 weeks. In STEP 1 (Wilding et al.

Average weight loss on semaglutide 2.4 mg weekly, from STEP 1 (Wilding et al.

Introduction Compounded semaglutide is the same active ingredient as Wegovy® and Ozempic®, made by 503A or 503B pharmacies and dispensed through telehealth platforms like…