Why Take Semaglutide: A Personalized Path to Sustainable Weight Management

Introduction

For many, the journey toward managing weight can feel like navigating a complex maze, often met with frustration and a cycle of temporary solutions. We understand this challenge deeply, recognizing that sustainable weight loss extends far beyond willpower and restrictive diets. For years, the medical community has searched for effective tools to support individuals in achieving significant, lasting health improvements. Enter semaglutide, a medication that has garnered considerable attention for its ability to redefine what’s possible in chronic weight management and metabolic health.

Originally developed to manage Type 2 Diabetes, semaglutide mimics a natural hormone in the body, profoundly impacting blood sugar regulation and, crucially, appetite control. Its emergence as a powerful aid in weight loss signifies a pivotal shift in how we approach obesity—acknowledging it as a complex, chronic metabolic disease rather than a simple failure of personal discipline.

In this comprehensive guide, we’ll delve into the multifaceted benefits of semaglutide, exploring the robust science behind its effectiveness, its various formulations, and the specific health conditions it can address. Our purpose is to illuminate why taking semaglutide could be a transformative step for individuals striving for a healthier lifestyle. We will also discuss who might be an ideal candidate for this therapy, its potential side effects, and how a personalized, medically supervised approach—like the programs we offer at TrimRx—can make this journey safe, effective, and tailored to your unique needs. By the end of this post, you’ll have a clear understanding of semaglutide’s potential and how it integrates into a holistic health strategy, empowering you to make informed decisions about your well-being.

The Science Behind Semaglutide: A Deep Dive into GLP-1 Receptor Agonists

Semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. To truly understand why taking semaglutide is so impactful, it’s essential to grasp how this hormone and its mimetic works within the body.

Understanding GLP-1: The Body’s Natural Regulator

GLP-1 is a natural hormone produced in the gut in response to eating. Its primary physiological roles include:

• Stimulating Insulin Release: When food is consumed, GLP-1 prompts the pancreas to release more insulin. Insulin is crucial for regulating blood sugar levels by helping glucose enter cells for energy. This action is glucose-dependent, meaning insulin is only released when blood sugar levels are elevated, reducing the risk of hypoglycemia (low blood sugar).
• Suppressing Glucagon Secretion: GLP-1 also inhibits the release of glucagon, another pancreatic hormone that typically raises blood sugar by signaling the liver to release stored glucose. By reducing glucagon, semaglutide helps maintain lower blood sugar levels.
• Slowing Gastric Emptying: GLP-1 delays the rate at which food leaves the stomach. This contributes to a feeling of fullness and can reduce overall food intake, as the body processes nutrients more slowly.
• Impacting Appetite and Satiety: Perhaps most significantly for weight management, GLP-1 interacts with specific receptors in the brain, particularly in the hypothalamus and brainstem. These interactions influence the neural circuits that regulate appetite and signal feelings of satiety, or fullness. By activating these pathways, semaglutide helps to reduce hunger cravings and decrease the desire to eat, leading to a natural reduction in calorie consumption.

How Semaglutide Mimics and Amplifies GLP-1

Semaglutide is designed to mimic the action of natural GLP-1 but with a crucial difference: it has a much longer half-life. While natural GLP-1 is quickly broken down by enzymes in the body, semaglutide is formulated to resist this degradation, remaining active for approximately one week. This extended action allows for once-weekly dosing, providing consistent therapeutic effects.

This prolonged activity means that semaglutide consistently signals the body to:

• Improve Glycemic Control: For individuals with Type 2 Diabetes, this leads to better management of blood sugar levels.
• Reduce Appetite and Cravings: By continuously activating satiety signals, semaglutide helps individuals feel fuller for longer, reducing the urge to snack or overeat.
• Facilitate Sustainable Weight Loss: The combined effects of reduced calorie intake, delayed gastric emptying, and improved metabolic function contribute to significant and sustained weight loss. Clinical studies have shown that individuals using semaglutide in conjunction with diet and exercise can achieve substantial reductions in body weight, often exceeding what is typically seen with lifestyle changes alone.

At TrimRx, our journey began with a shared vision to help individuals embrace healthier lifestyles by merging cutting-edge telehealth innovations with effective weight loss solutions. We understand that this sophisticated mechanism of action is a cornerstone of why taking semaglutide can be a game-changer for many seeking meaningful health transformation.

Why Take Semaglutide for Weight Management: The Evidence and Impact

The effectiveness of semaglutide for weight loss has been a topic of extensive research, revealing compelling results that underscore why taking semaglutide is a valuable option for chronic weight management.

Significant Weight Reduction

Clinical trials have consistently demonstrated semaglutide’s powerful impact on body weight. For instance, studies involving adults with obesity or overweight (without Type 2 Diabetes) showed that participants taking semaglutide alongside diet and exercise achieved an average weight loss of 15% to 20% of their body weight over 68 weeks. This stands in stark contrast to participants who only made lifestyle changes, who typically lost about 2-3% of their body weight. These findings highlight that semaglutide provides a substantial advantage in achieving clinically meaningful weight loss.

It’s crucial to understand that while semaglutide is highly effective, it is not a “miracle drug.” Its success is maximized when integrated into a broader strategy that includes sustained commitment to dietary improvements and regular physical activity. We believe that sustainable weight loss should be achieved through science, empathy, and a transparent approach, and semaglutide represents a powerful, science-backed tool within that framework.

Addressing the Chronic Nature of Obesity

Obesity is a complex, multifactorial chronic disease. For many, simply relying on “willpower” or conventional diets proves insufficient for long-term management. The body often adapts to weight loss efforts by increasing hunger hormones and decreasing satiety signals, making sustained weight reduction incredibly difficult. Semaglutide helps to re-regulate these physiological responses, offering a much-needed tool in the ongoing battle against weight regain.

The evidence suggests that when semaglutide treatment is discontinued, weight regain can occur. This reinforces the understanding of obesity as a chronic condition requiring lifelong management, often with ongoing medical support. Our platform is a user-friendly and supportive space where individuals receive personalized, medically supervised care—all designed to make sustainable weight loss attainable and tailored to the individual. We offer compassionate care that respects every individual’s unique journey, combining advanced medical science with modern technology to support these long-term goals.

Beyond the Scale: Health Improvements Associated with Weight Loss

The benefits of semaglutide extend beyond just aesthetic changes. Significant weight loss, aided by semaglutide, can lead to a cascade of positive health outcomes, including:

• Improved Metabolic Health: Lowering body weight can lead to better insulin sensitivity, reducing the risk or improving the management of Type 2 Diabetes.
• Reduced Cardiovascular Risk: Excess weight is a major risk factor for heart disease. Weight loss can improve blood pressure, cholesterol levels, and overall cardiovascular health, significantly lowering the risk of heart attack and stroke. Clinical trials, such as SUSTAIN-6, have shown that semaglutide can reduce the risk of major adverse cardiovascular events in individuals with Type 2 Diabetes and established cardiovascular disease.
• Decreased Risk of Weight-Related Cancers: Obesity is linked to an increased risk of several types of cancer. Achieving and maintaining a healthier weight can help mitigate these risks.
• Enhanced Quality of Life: Beyond clinical markers, weight loss can improve mobility, reduce joint pain, improve sleep quality (e.g., reducing sleep apnea), and significantly boost self-esteem and mental well-being.

Considering why taking semaglutide is a powerful choice for weight management, it’s not just about the number on the scale but the holistic improvement in health and quality of life it can facilitate. If you’re wondering if you qualify for a personalized prescription weight loss plan, we encourage you to take our free assessment quiz to see if you qualify.

Understanding Semaglutide Formulations and Our Offerings

Semaglutide is available in different formulations, designed to cater to individual needs and preferences. Understanding these options is key to comprehending why taking semaglutide may be prescribed in a specific manner.

Types of Semaglutide Products

Currently, semaglutide is available in both injectable and oral forms, each with distinct administration guidelines:

Subcutaneous Semaglutide (Injectable)

This is the most common form of semaglutide for weight loss and Type 2 Diabetes management.

• Ozempic®: An FDA-approved medication primarily indicated for improving blood sugar control in adults with Type 2 Diabetes and reducing the risk of major cardiovascular events in adults with Type 2 Diabetes and established heart disease. It is administered as a once-weekly subcutaneous injection.
• Wegovy®: An FDA-approved medication specifically indicated for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity. It is also administered as a once-weekly subcutaneous injection.
• Compounded Semaglutide: Our compounded semaglutide offers a similar mechanism of action, provided through our network of FDA-registered and inspected pharmacies. It is also administered as a once-weekly subcutaneous injection. It’s important to note that compounded medications are prepared by a licensed pharmacy for an individual patient based on a prescription from a licensed healthcare provider, and are not FDA-approved like branded medications.

For subcutaneous injections, the medication is administered under the skin of the abdomen, thigh, or upper arm, with sites rotated weekly. The dosage typically starts low and is gradually increased over several months to minimize potential side effects and enhance tolerability, always under the guidance of a healthcare professional.

Oral Semaglutide (Tablet)

For those who prefer not to inject, an oral tablet formulation is available.

• Rybelsus®: An FDA-approved medication primarily indicated for improving blood sugar control in adults with Type 2 Diabetes.
• Oral Semaglutide (Compounded): We also offer compounded oral semaglutide as part of our personalized programs, prepared by FDA-registered and inspected pharmacies. Like other compounded medications, it is not FDA-approved.

Oral semaglutide typically requires specific administration instructions, such as taking it on an empty stomach with a small amount of water, at least 30 minutes before the first food, beverage, or other oral medications of the day. This is to optimize its absorption, as food and increased fluid intake can affect its bioavailability.

TrimRx’s Comprehensive Product Offerings

At TrimRx, we are committed to providing personalized, medically supervised care. Our approach ensures that you receive the most appropriate treatment plan for your specific needs. When considering why taking semaglutide with TrimRx is a clear choice, our wide array of options stands out:

Personalized Weight Loss Program (Requires Quiz)

Our prescription weight loss medications are part of a personalized program designed to ensure optimal outcomes under medical supervision. To determine your eligibility and receive a tailored treatment plan, we invite you to take our free assessment quiz. This program may include:

• Compounded Semaglutide
• Oral Semaglutide
• Ozempic®
• Compounded Tirzepatide
• Oral Tirzepatide
• Mounjaro®
• Zepbound®
• Wegovy®

Our comprehensive service includes doctor consultations, necessary lab work, the medication itself, unlimited support throughout your journey, and convenient shipping, all with no hidden fees. We work exclusively with FDA-registered and inspected pharmacies for the shipping of these weight loss medications, ensuring your safety and adherence to regulatory standards. It must be clear that TrimRx partners with these pharmacies for the shipping of weight loss medications and does not provide actual medical supervision; medical supervision is provided by licensed healthcare providers who are part of the TrimRx network.

Quick-Access Supplements (No Quiz Required)

In addition to our prescription programs, we offer immediate support supplements designed to complement your overall wellness during your weight loss journey. These do not require a medical assessment and can be purchased directly:

• GLP-1 Daily Support: Designed to support your body’s natural processes.
• Weight Loss Boost: Crafted to provide additional reinforcement for your weight management efforts.

We are dedicated to transparent service, highlighting that our approach remains consistent regardless of dosage changes, always prioritizing your health and well-being.

Who Should Consider Semaglutide? Eligibility and Considerations

Deciding why taking semaglutide is right for you involves a careful assessment of your health profile, medical history, and weight loss goals. This medication is not for everyone, and a personalized evaluation by a healthcare provider is always the essential first step.

FDA Guidelines for Prescription Semaglutide for Weight Loss

The FDA has established specific criteria for individuals to qualify for prescription semaglutide for chronic weight management (Wegovy®):

• A Body Mass Index (BMI) of 30 kg/m² or greater (considered obesity).
• A BMI of 27 kg/m² or greater (considered overweight) with at least one weight-related comorbidity, such as:
  • Type 2 Diabetes
  • High blood pressure (hypertension)
  • High cholesterol (dyslipidemia)
  • Obstructive sleep apnea

These guidelines ensure that semaglutide is prescribed to individuals who can benefit most from its profound effects on weight and metabolic health, offering a medically sound reason why taking semaglutide can be a critical intervention.

The Importance of Medical Supervision and Personalized Assessment

Given its powerful pharmacological actions and potential side effects, semaglutide should only be used under strict medical supervision. A thorough medical evaluation helps determine if semaglutide is a safe and appropriate option for you. This assessment typically includes:

• Review of Medical History: Your healthcare provider will ask about your personal and family history of certain conditions, including thyroid cancer, pancreatitis, gallbladder disease, and endocrine disorders (such as Multiple Endocrine Neoplasia syndrome type 2 or MEN 2).
• Current Medications: To prevent potential drug interactions, a comprehensive review of all medications, supplements, and herbal remedies you are currently taking is crucial.
• Lab Work: Blood tests may be necessary to assess your overall health, kidney function, and blood sugar levels.

At TrimRx, we emphasize that a personalized approach is paramount. Our easy-to-use platform streamlines this process, connecting you with licensed healthcare providers who can conduct a thorough evaluation. We believe that sustainable weight loss should be achieved through science, empathy, and a transparent approach, which is why our personalized assessment is a vital first step. To discover if you meet the criteria for our personalized prescription weight loss programs, we encourage you to take our free assessment quiz. This helps us craft a plan that is truly tailored to your unique journey.

Conditions Where Semaglutide is Generally Not Recommended

While effective for many, semaglutide is contraindicated or generally not recommended for individuals with certain health conditions due to potential risks. These include:

• Personal or Family History of Medullary Thyroid Carcinoma (MTC): Semaglutide carries a boxed warning regarding the risk of thyroid C-cell tumors.
• Multiple Endocrine Neoplasia syndrome type 2 (MEN 2): A genetic disorder that increases the risk of certain endocrine gland tumors, including MTC.
• History of Pancreatitis: Semaglutide can increase the risk of pancreatitis (inflammation of the pancreas).
• Severe Gastrointestinal Disease: Due to its effect on gastric emptying, individuals with severe gastroparesis or other significant gastrointestinal issues may not be suitable candidates.
• Diabetic Retinopathy: Individuals with a history of diabetic retinopathy should be carefully monitored, as rapid improvements in blood sugar control can sometimes worsen this condition.
• Pregnancy and Breastfeeding: Weight loss medications are generally not recommended during pregnancy, and their use during breastfeeding has not been well-studied. It’s often advised to discontinue semaglutide at least two months prior to planning a pregnancy.

Our brand is empathetic, innovative, trustworthy, supportive, results-oriented, and personalized. We offer compassionate care that respects every individual’s unique journey, always prioritizing safety and clear communication about who can and cannot safely use our programs.

Navigating Potential Side Effects and Safety Considerations

Understanding potential side effects and safety considerations is a critical aspect of deciding why taking semaglutide is a responsible choice. While generally well-tolerated, like all medications, semaglutide can cause adverse reactions.

Common Side Effects

Most side effects associated with semaglutide are mild to moderate, especially during the initial titration phase when the body is adjusting to the medication. These often involve the gastrointestinal system:

• Nausea: This is one of the most frequently reported side effects.
• Vomiting: Can occur, particularly if doses are increased too quickly.
• Diarrhea or Constipation: Changes in bowel habits are common.
• Abdominal Pain or Distension: Discomfort in the stomach area.
• Headache: Mild headaches can be reported.
• Fatigue: Some individuals may experience tiredness.
• Dizziness: Can occur, often related to hydration or blood sugar changes.

These gastrointestinal issues are often manageable by starting with a low dose and gradually increasing it over several weeks, a strategy employed in all our personalized weight loss programs. Maintaining good hydration by drinking plenty of water and eating water-rich fruits and vegetables is also important, especially if experiencing vomiting or diarrhea.

More Serious Side Effects and Warning Signs

While less common, it’s important to be aware of potentially serious side effects. Individuals should report any of the following to their healthcare provider immediately:

• Pancreatitis: Severe stomach pain that radiates to the back, accompanied by nausea, vomiting, or fever.
• Gallbladder Problems: Symptoms like severe stomach pain, nausea, vomiting, fever, or yellowing of the eyes or skin can indicate issues like gallstones.
• Kidney Injury: Decreased urination, swelling in the ankles, hands, or feet, or signs of dehydration (increased thirst, dry mouth, headache, feeling faint).
• Thyroid C-cell Tumors (including Medullary Thyroid Carcinoma): A new lump or swelling in the neck, trouble swallowing, hoarseness that doesn’t go away, or trouble breathing. This is why a personal or family history of MTC or MEN 2 is a contraindication.
• Severe Allergic Reactions: Symptoms like a rash, itching, hives, or swelling of the face, lips, tongue, or throat.
• Changes in Vision: Blurred vision or any other vision changes, especially in individuals with diabetic retinopathy.
• Increased Heart Rate: Persistent fast or pounding heartbeat while at rest.
• Thoughts of Suicide or Self-Harm: Worsening mood, feelings of depression, or any suicidal thoughts or behaviors.

Safety and Compliance at TrimRx

Your safety is our utmost priority. When you consider why taking semaglutide through TrimRx is a secure option, our commitment to stringent safety protocols is clear:

• Medically Supervised Programs: Our programs require doctor consultations and lab work to ensure that semaglutide or any other medication is appropriate and safe for your unique health profile. Medical supervision is provided by licensed healthcare providers who are part of the TrimRx network.
• FDA-Registered and Inspected Pharmacies: We partner exclusively with FDA-registered and inspected pharmacies for the shipping of our weight loss medications. This ensures that the medications you receive meet high standards of quality and safety. We clearly distinguish between FDA-approved branded medications like Ozempic® and Wegovy®, and compounded medications which are not FDA-approved but are prepared by these regulated pharmacies.
• Ongoing Support: We offer unlimited support to address any concerns or side effects you may experience throughout your weight loss journey. Our team is here to provide guidance and assistance every step of the way.
• Transparent Service: We believe in a transparent approach, providing comprehensive service that includes all necessary components for a successful and safe experience, with no hidden fees.

Before any procedure or surgery, it is crucial to inform your care team that you are taking semaglutide, as it can delay gastric emptying, which may have anesthetic implications. Always communicate openly with your healthcare provider about any symptoms or concerns. For personalized guidance on whether you qualify for our prescription weight loss medications, we invite you to take our free assessment quiz.

The TrimRx Difference: A Personalized and Supportive Journey

At TrimRx, we understand that embarking on a weight loss journey is deeply personal and often challenging. Our entire approach is built around providing a supportive, effective, and clinically proven path to help individuals achieve their health goals. When considering why taking semaglutide with TrimRx stands apart, it’s our dedication to personalized, medically supervised care that truly defines our service.

Our Brand Story and Values

Our journey began with a shared vision: to empower individuals to embrace healthier lifestyles. We merged cutting-edge telehealth innovations with effective weight loss solutions, creating a platform that is both user-friendly and deeply supportive. We firmly believe that sustainable weight loss should be achieved through science, empathy, and a transparent approach. These values are at the core of everything we do.

We recognize that each person’s journey is unique, which is why our brand personality is empathetic, innovative, trustworthy, supportive, results-oriented, and personalized. We combine advanced medical science with modern technology to deliver compassionate care that respects your individual needs and circumstances.

A Comprehensive Service Model

We designed our programs to eliminate barriers and provide a seamless experience, ensuring that when you decide why taking semaglutide is right for you, you have all the necessary support. Our comprehensive service includes:

• Doctor Consultations: Access to licensed healthcare providers who conduct thorough evaluations and create personalized treatment plans. These consultations are crucial for determining eligibility, discussing your health history, and addressing any concerns.
• Medication Management: Prescription medications, including Compounded Semaglutide, Oral Semaglutide, Ozempic®, Wegovy®, and other advanced options like Tirzepatide formulations (Compounded Tirzepatide, Oral Tirzepatide, Mounjaro®, Zepbound®), are sourced through FDA-registered and inspected pharmacies. We ensure clear communication regarding the FDA status of all medications—distinguishing between FDA-approved branded drugs and compounded alternatives.
• Lab Work: Essential lab tests are integrated into our programs to monitor your health and ensure the safety and effectiveness of your treatment.
• Unlimited Support: Our team provides continuous guidance, answering questions and offering encouragement every step of the way. We are committed to being a reliable partner in your health transformation.
• Convenient Shipping: Medications are shipped directly to your door, simplifying access and ensuring continuity of care.
• No Hidden Fees: Our transparent approach means you know exactly what to expect, allowing you to focus on your health without financial surprises.

Our commitment to transparent service remains consistent regardless of dosage changes. This holistic approach is designed to make sustainable weight loss attainable and tailored to the individual, reinforcing why taking semaglutide within a structured, supportive environment is so beneficial.

Beyond Prescription Medications: Quick-Access Support

We also understand that some individuals may be looking for immediate support or wish to complement their weight loss efforts with non-prescription options. For those instances, we offer quick-access supplements that do not require a quiz:

• GLP-1 Daily Support: This supplement is formulated to provide daily assistance to your body’s wellness, supporting your journey from within.
• Weight Loss Boost: Designed to give an extra push to your weight management efforts, these supplements are available for immediate purchase to support overall wellness.

These options reflect our dedication to providing a range of solutions that cater to diverse needs, solidifying our role as a comprehensive partner in health.

Your Next Step Towards a Healthier You

Embarking on a weight loss journey, especially with powerful tools like semaglutide, requires careful consideration and professional guidance. We are here to simplify that process and provide the expert care you deserve. If you’re ready to explore whether a personalized, medically supervised weight loss program with semaglutide is right for you, we encourage you to take our free assessment quiz today. This is your opportunity to understand your options, receive a tailored plan, and begin a transformative journey with a trusted partner by your side.

Conclusion

The decision of why taking semaglutide is a significant one, rooted in its scientifically proven ability to address chronic weight management and improve metabolic health. We have explored how this GLP-1 receptor agonist mimics natural hormones to effectively reduce appetite, slow digestion, and regulate blood sugar, leading to substantial and sustainable weight loss for many individuals. Beyond the scale, semaglutide, when combined with dedicated lifestyle changes, opens doors to improved cardiovascular health, reduced risk of various chronic diseases, and an overall enhancement in quality of life.

At TrimRx, we are committed to providing a transparent, empathetic, and science-backed pathway to achieving your health goals. Our personalized approach, encompassing doctor consultations, necessary lab work, medication from FDA-registered and inspected pharmacies, and unlimited support, ensures that your journey is not only effective but also safe and tailored to your unique needs. We understand the complexities of weight management and stand ready as your trusted partner, offering both cutting-edge prescription solutions and immediate support through our specialized supplements like GLP-1 Daily Support and Weight Loss Boost.

Your health journey is personal, and the path to sustainable weight loss should reflect that. If you are struggling with weight-related issues and believe semaglutide could be the right tool for you, we invite you to take the crucial first step. Take our free assessment quiz today to determine your eligibility for our personalized weight loss programs and discover how we can help you achieve lasting health and well-being.

FAQ

How long does it typically take to see results with semaglutide?

The timeline for seeing results with semaglutide can vary among individuals, but many people begin to experience changes in appetite and weight within the first few weeks of starting treatment. Significant weight loss, as demonstrated in clinical trials, often occurs over several months, with average weight reductions observed around 68 weeks. The gradual dose escalation strategy helps to maximize effectiveness while minimizing side effects, allowing your body to adjust steadily. Consistency with your medication and adherence to lifestyle modifications are key factors in achieving optimal and sustained results.

Are there any specific dietary restrictions or recommendations while taking semaglutide?

While semaglutide helps reduce appetite and calorie intake, it works most effectively when combined with a healthy diet and regular physical activity. There are no strict dietary restrictions imposed by semaglutide itself, but a balanced, nutrient-dense eating plan is highly recommended. Focusing on lean proteins, whole grains, fruits, and vegetables can support overall health and enhance weight loss. It’s also important to stay well-hydrated. Since semaglutide slows gastric emptying, some individuals find that eating smaller, more frequent meals and avoiding high-fat or very rich foods can help mitigate potential gastrointestinal side effects like nausea or indigestion.

What makes TrimRx’s approach to semaglutide different from other providers?

At TrimRx, our distinct approach is centered on personalized, medically supervised care, integrating cutting-edge telehealth with a comprehensive support system. We stand out through our commitment to transparency, offering doctor consultations, lab work, medication (including both branded FDA-approved options like Ozempic® and Wegovy®, and compounded alternatives from FDA-registered and inspected pharmacies), unlimited support, and shipping—all with no hidden fees. We prioritize your safety and individualized needs, ensuring a tailored plan and compassionate care every step of your journey. We respect that medical supervision is provided by licensed healthcare providers within the TrimRx network.

Can I take semaglutide if I don’t have diabetes?

Yes, semaglutide is approved for weight management in individuals who do not have Type 2 Diabetes but meet specific criteria. For example, the branded version Wegovy® is FDA-approved for chronic weight management in adults with obesity (BMI of 30 kg/m² or greater) or those who are overweight (BMI of 27 kg/m² or greater) with at least one weight-related medical condition such as high blood pressure, high cholesterol, or obstructive sleep apnea. Our personalized assessment quiz can help determine your eligibility for our prescription weight loss medications, including semaglutide, based on your health profile and medical history.