Petrelintide is an investigational weight-loss injection that works through amylin, a satiety hormone separate from the GLP-1 pathway, and its main selling point is…

VK2735 is an investigational obesity drug from Viking Therapeutics with a notable flexibility: it’s being developed in both an injectable form and an oral…

Mazdutide is a weekly weight-loss injection that’s notable for a milestone: it’s the world’s first approved drug to combine GLP-1 and glucagon activity in…

MariTide is an investigational weight-loss injection from Amgen with an unusual selling point: you’d take it just once a month, rather than once a…

Danuglipron was Pfizer’s attempt at an oral GLP-1 weight-loss pill, and the short answer to what happened is that Pfizer discontinued it in April…

Efpeglenatide is a once-weekly GLP-1 medication that stands out for one big reason: it’s backed by a major clinical trial showing it reduces the…

Cagrilintide is a once-weekly injectable weight-loss drug that works through amylin, a satiety hormone that’s completely separate from the GLP-1 pathway most obesity drugs…

Pemvidutide is an investigational weight-loss and liver drug that hits two hormone targets at once: GLP-1 (which curbs appetite) and glucagon (which increases energy…

Losing a significant amount of weight changes more than your body, it changes the dynamics of your closest relationship, and talking openly with your…