Weight Loss

CagriSema’s side effects are mostly gastrointestinal, and while they’re common, the large majority are mild to moderate and fade over time. In the phase…

Petrelintide is an investigational weight-loss injection that works through amylin, a satiety hormone separate from the GLP-1 pathway, and its main selling point is…

VK2735 is an investigational obesity drug from Viking Therapeutics with a notable flexibility: it’s being developed in both an injectable form and an oral…

MariTide is an investigational weight-loss injection from Amgen with an unusual selling point: you’d take it just once a month, rather than once a…

Danuglipron was Pfizer’s attempt at an oral GLP-1 weight-loss pill, and the short answer to what happened is that Pfizer discontinued it in April…

Cagrilintide is a once-weekly injectable weight-loss drug that works through amylin, a satiety hormone that’s completely separate from the GLP-1 pathway most obesity drugs…

Chafing and irritation around the vulva, groin, and inner thighs is a common and very manageable nuisance while you’re losing weight, and a few…

If you’re losing weight on a GLP-1 medication around the same time you’re approaching or going through menopause, and your vulvar and vaginal tissues…

If you’re waiting on retatrutide, here’s the realistic answer: it isn’t available yet, and based on Eli Lilly’s published trial timeline, an FDA submission…